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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
25.45
Human Site:
T304
Identified Species:
56
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
T304
K
V
E
G
T
E
P
T
T
A
F
N
L
F
V
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
T576
K
V
E
G
T
E
P
T
T
A
F
N
L
F
V
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
T532
K
V
E
G
T
E
P
T
T
A
F
N
L
F
V
Dog
Lupus familis
XP_850477
699
75739
T293
K
V
E
A
T
E
P
T
T
S
F
N
L
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
T306
K
V
E
G
S
E
P
T
T
P
F
N
L
F
I
Rat
Rattus norvegicus
P13383
713
77129
T308
K
I
E
G
S
E
P
T
T
P
F
N
L
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
A245
K
T
E
P
I
E
P
A
S
A
F
N
L
F
I
Chicken
Gallus gallus
P15771
694
75622
A278
K
K
K
T
E
T
P
A
S
A
F
S
L
F
V
Frog
Xenopus laevis
P20397
651
70177
S230
K
T
K
T
D
T
A
S
E
G
L
S
I
F
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
S69
K
V
V
K
P
Q
E
S
D
D
S
S
S
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
E83
S
E
A
E
T
K
K
E
E
S
K
D
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
100
100
86.6
N.A.
80
73.3
N.A.
60
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
73.3
66.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
19
0
46
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
10
0
10
0
0
0
% D
% Glu:
0
10
64
10
10
64
10
10
19
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
73
0
0
82
0
% F
% Gly:
0
0
0
46
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
0
10
0
37
% I
% Lys:
91
10
19
10
0
10
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
0
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
64
0
0
0
% N
% Pro:
0
0
0
10
10
0
73
0
0
19
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
19
0
0
19
19
19
10
28
19
10
10
% S
% Thr:
0
19
0
19
46
19
0
55
55
0
0
0
0
0
0
% T
% Val:
0
55
10
0
0
0
0
0
0
0
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _