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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
32.73
Human Site:
T394
Identified Species:
72
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
T394
K
K
E
R
D
A
R
T
L
L
A
K
N
L
P
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
T666
K
K
E
R
D
A
R
T
L
L
A
K
N
L
P
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
T622
K
K
E
R
D
A
R
T
L
L
A
K
N
L
P
Dog
Lupus familis
XP_850477
699
75739
T383
K
K
D
R
D
A
R
T
L
L
A
K
N
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
T396
K
K
V
R
A
A
R
T
L
L
A
K
N
L
S
Rat
Rattus norvegicus
P13383
713
77129
T398
K
K
V
R
A
A
R
T
L
L
A
K
N
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
T335
K
K
E
R
D
A
R
T
L
F
V
K
N
L
P
Chicken
Gallus gallus
P15771
694
75622
T372
K
K
E
R
D
A
R
T
L
F
V
K
N
L
P
Frog
Xenopus laevis
P20397
651
70177
T326
K
K
E
R
D
S
R
T
L
F
V
K
N
I
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
E152
E
S
S
D
D
S
D
E
D
E
S
E
E
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
E166
Q
K
N
E
E
T
E
E
P
A
T
I
F
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
86.6
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
86.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
73
0
0
0
10
55
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
73
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
55
10
10
0
10
19
0
10
0
10
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
28
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
82
91
0
0
0
0
0
0
0
0
0
82
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
82
55
0
0
0
73
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
82
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
64
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
82
0
0
82
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
19
0
0
0
0
10
0
0
0
19
% S
% Thr:
0
0
0
0
0
10
0
82
0
0
10
0
0
0
0
% T
% Val:
0
0
19
0
0
0
0
0
0
0
28
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _