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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCL All Species: 21.21
Human Site: T76 Identified Species: 46.67
UniProt: P19338 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19338 NP_005372.2 710 76614 T76 T K K V A V A T P A K K A A V
Chimpanzee Pan troglodytes XP_516145 1006 108719 T347 T K K V A V A T P A K K A A V
Rhesus Macaque Macaca mulatta XP_001116949 938 100743 T303 T K K V A V A T P A K K A A V
Dog Lupus familis XP_850477 699 75739 T60 T K K V A V A T P A K K A V V
Cat Felis silvestris
Mouse Mus musculus P09405 707 76705 T76 T K K A A V P T P A K K A A V
Rat Rattus norvegicus P13383 713 77129 T76 T K K A A V P T P A K K A A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509329 631 67414 A63 G K K A V A A A A T P A K K A
Chicken Gallus gallus P15771 694 75622 V55 K K Q Q K A A V T P A K K A A
Frog Xenopus laevis P20397 651 70177 Q87 N G K Q A K K Q E S E E E E D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797746 400 43419
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P27476 414 44517
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 74.7 91.6 N.A. 83.9 84.2 N.A. 65.6 63.2 55.6 N.A. N.A. N.A. N.A. N.A. 24
Protein Similarity: 100 70.4 75.4 94.9 N.A. 90.1 90.4 N.A. 73.9 76 68.4 N.A. N.A. N.A. N.A. N.A. 32.8
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 26.6 13.3 N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 33.3 33.3 N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 28 64 19 55 10 10 55 10 10 55 55 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 10 10 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 73 73 0 10 10 10 0 0 0 55 64 19 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 19 0 55 10 10 0 0 0 0 % P
% Gln: 0 0 10 19 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % S
% Thr: 55 0 0 0 0 0 0 55 10 10 0 0 0 0 0 % T
% Val: 0 0 0 37 10 55 0 10 0 0 0 0 0 10 55 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _