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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HK1
All Species:
33.33
Human Site:
T473
Identified Species:
81.48
UniProt:
P19367
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19367
NP_000179.2
917
102486
T473
Q
H
R
Q
I
E
E
T
L
A
H
F
H
L
T
Chimpanzee
Pan troglodytes
XP_001169069
971
108044
T527
Q
H
R
Q
I
E
E
T
L
A
H
F
H
L
T
Rhesus Macaque
Macaca mulatta
XP_001110269
921
102627
T477
Q
H
R
Q
I
E
E
T
L
A
H
F
H
L
T
Dog
Lupus familis
XP_536376
1073
118993
T629
Q
H
R
Q
I
E
E
T
L
A
H
F
R
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P17710
974
108284
T529
Q
H
R
Q
I
E
E
T
L
S
H
F
R
L
S
Rat
Rattus norvegicus
P05708
918
102389
T473
Q
H
R
Q
I
E
E
T
L
A
H
F
R
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989432
917
102697
T473
Q
H
R
L
I
D
E
T
L
A
E
F
K
L
T
Frog
Xenopus laevis
NP_001096656
916
102431
T473
Q
R
R
Q
I
D
E
T
L
E
E
F
K
L
S
Zebra Danio
Brachydanio rerio
NP_998417
918
102810
T473
Q
E
R
Q
I
A
E
T
L
E
E
F
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFT7
486
53467
Y100
T
G
K
E
R
G
K
Y
L
A
L
D
L
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
96.9
81.7
N.A.
85.8
92.5
N.A.
N.A.
87.5
85.9
85.4
N.A.
25.9
N.A.
N.A.
N.A.
Protein Similarity:
100
93.6
97.5
83.8
N.A.
91
97.2
N.A.
N.A.
94.6
93.6
92.9
N.A.
36.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
N.A.
73.3
60
66.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
73.3
66.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
70
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
10
0
60
90
0
0
20
30
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
10
% G
% His:
0
70
0
0
0
0
0
0
0
0
60
0
30
0
0
% H
% Ile:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
0
0
20
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
100
0
10
0
10
90
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
90
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
90
0
10
0
0
0
0
0
0
0
40
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
30
% S
% Thr:
10
0
0
0
0
0
0
90
0
0
0
0
0
0
60
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _