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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HK1
All Species:
36.36
Human Site:
Y199
Identified Species:
88.89
UniProt:
P19367
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19367
NP_000179.2
917
102486
Y199
A
I
K
K
R
G
D
Y
D
A
N
I
V
A
V
Chimpanzee
Pan troglodytes
XP_001169069
971
108044
Y253
A
I
K
K
R
G
D
Y
D
A
N
I
V
A
V
Rhesus Macaque
Macaca mulatta
XP_001110269
921
102627
Y203
A
I
K
K
R
G
D
Y
D
A
N
I
V
A
V
Dog
Lupus familis
XP_536376
1073
118993
Y355
A
I
K
K
R
G
D
Y
D
A
N
I
V
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P17710
974
108284
Y255
A
I
K
K
R
G
D
Y
D
A
N
I
V
A
V
Rat
Rattus norvegicus
P05708
918
102389
Y199
A
I
K
K
R
G
D
Y
D
A
N
I
V
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989432
917
102697
Y199
A
I
K
K
R
G
D
Y
D
A
D
I
M
A
V
Frog
Xenopus laevis
NP_001096656
916
102431
Y199
A
I
K
K
R
G
D
Y
E
A
D
I
M
A
V
Zebra Danio
Brachydanio rerio
NP_998417
918
102810
Y199
A
I
K
K
R
G
D
Y
E
A
D
I
M
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFT7
486
53467
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
96.9
81.7
N.A.
85.8
92.5
N.A.
N.A.
87.5
85.9
85.4
N.A.
25.9
N.A.
N.A.
N.A.
Protein Similarity:
100
93.6
97.5
83.8
N.A.
91
97.2
N.A.
N.A.
94.6
93.6
92.9
N.A.
36.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
80
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
90
0
0
0
0
0
0
0
0
90
0
0
0
90
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
90
0
70
0
30
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
90
0
0
0
0
0
0
0
0
0
90
0
0
0
% I
% Lys:
0
0
90
90
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
90
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _