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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2C
All Species:
38.18
Human Site:
S209
Identified Species:
64.62
UniProt:
P19387
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19387
NP_116558.1
275
31441
S209
E
W
P
K
S
E
Y
S
E
L
D
E
D
E
S
Chimpanzee
Pan troglodytes
XP_510992
242
27800
E177
W
P
K
S
E
Y
S
E
L
D
E
D
E
S
Q
Rhesus Macaque
Macaca mulatta
XP_001098211
257
29446
L192
E
Y
D
P
D
N
A
L
R
H
T
V
Y
P
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97760
275
31292
S209
E
G
P
K
S
E
Y
S
E
L
D
E
D
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511558
352
38872
S286
E
W
P
K
S
E
Y
S
E
I
D
E
D
E
A
Chicken
Gallus gallus
XP_414001
275
31371
S209
E
W
P
K
S
E
Y
S
E
I
D
E
E
D
A
Frog
Xenopus laevis
NP_001084998
275
31317
S209
E
W
P
K
S
E
Y
S
E
I
D
E
E
E
A
Zebra Danio
Brachydanio rerio
NP_956215
275
31337
S209
E
W
P
K
S
E
Y
S
E
I
E
E
D
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477419
275
31224
T210
E
W
P
K
S
E
H
T
E
L
E
D
D
Q
Y
Honey Bee
Apis mellifera
XP_624836
276
31595
S209
E
W
P
K
S
E
Y
S
E
L
E
E
D
Q
Y
Nematode Worm
Caenorhab. elegans
NP_492361
282
32359
S215
E
W
P
R
S
D
H
S
S
L
P
E
D
S
T
Sea Urchin
Strong. purpuratus
XP_001176308
275
30823
T207
E
W
P
K
S
E
F
T
E
V
D
E
D
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39211
319
35443
I213
D
E
E
K
I
D
L
I
E
S
S
P
T
K
V
Baker's Yeast
Sacchar. cerevisiae
P16370
318
35279
Q203
D
S
A
K
E
W
P
Q
S
K
N
C
E
Y
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
77.8
N.A.
N.A.
96.7
N.A.
N.A.
69.5
96.3
93.8
89.8
N.A.
69
69.9
54.9
71.6
Protein Similarity:
100
86.9
81.4
N.A.
N.A.
97
N.A.
N.A.
74.7
99.6
98.1
96.7
N.A.
89
89.8
75.1
86.1
P-Site Identity:
100
0
6.6
N.A.
N.A.
93.3
N.A.
N.A.
86.6
73.3
80
73.3
N.A.
60
80
53.3
66.6
P-Site Similarity:
100
20
13.3
N.A.
N.A.
93.3
N.A.
N.A.
100
100
100
86.6
N.A.
93.3
93.3
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.4
40.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
57.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
15
0
8
0
8
15
0
0
0
8
43
15
58
8
0
% D
% Glu:
79
8
8
0
15
65
0
8
72
0
29
65
29
29
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
15
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
29
0
0
0
0
0
% I
% Lys:
0
0
8
79
0
0
0
0
0
8
0
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
8
8
8
36
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
72
8
0
0
8
0
0
0
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
15
8
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
72
0
8
58
15
8
8
0
0
15
15
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
8
0
8
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
15
% V
% Trp:
8
65
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
50
0
0
0
0
0
8
8
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _