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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2C
All Species:
36.06
Human Site:
T102
Identified Species:
61.03
UniProt:
P19387
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19387
NP_116558.1
275
31441
T102
P
E
C
S
V
E
F
T
L
D
V
R
C
N
E
Chimpanzee
Pan troglodytes
XP_510992
242
27800
D77
L
D
V
R
C
N
E
D
Q
T
R
H
V
T
S
Rhesus Macaque
Macaca mulatta
XP_001098211
257
29446
E92
S
R
D
C
T
C
E
E
F
C
P
E
C
S
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97760
275
31292
T102
P
E
C
S
V
E
F
T
L
D
V
R
C
N
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511558
352
38872
T179
P
E
C
S
V
E
F
T
L
D
V
R
C
N
E
Chicken
Gallus gallus
XP_414001
275
31371
T102
P
E
C
S
V
E
F
T
L
D
V
R
C
N
E
Frog
Xenopus laevis
NP_001084998
275
31317
T102
P
E
C
S
V
E
F
T
L
D
V
R
C
T
E
Zebra Danio
Brachydanio rerio
NP_956215
275
31337
T102
P
E
C
S
V
E
L
T
L
D
V
R
C
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477419
275
31224
T102
P
E
C
S
V
E
F
T
L
D
V
K
C
S
E
Honey Bee
Apis mellifera
XP_624836
276
31595
T102
P
E
C
S
V
E
F
T
L
D
V
K
C
T
E
Nematode Worm
Caenorhab. elegans
NP_492361
282
32359
I102
D
E
C
S
I
P
F
I
L
Q
M
K
C
K
D
Sea Urchin
Strong. purpuratus
XP_001176308
275
30823
S102
S
D
C
S
V
E
L
S
L
D
V
K
C
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39211
319
35443
R107
E
F
C
S
V
E
F
R
L
S
S
K
C
V
T
Baker's Yeast
Sacchar. cerevisiae
P16370
318
35279
T100
D
K
C
S
V
V
L
T
L
Q
A
F
G
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
77.8
N.A.
N.A.
96.7
N.A.
N.A.
69.5
96.3
93.8
89.8
N.A.
69
69.9
54.9
71.6
Protein Similarity:
100
86.9
81.4
N.A.
N.A.
97
N.A.
N.A.
74.7
99.6
98.1
96.7
N.A.
89
89.8
75.1
86.1
P-Site Identity:
100
0
6.6
N.A.
N.A.
100
N.A.
N.A.
100
100
93.3
86.6
N.A.
86.6
86.6
40
53.3
P-Site Similarity:
100
6.6
13.3
N.A.
N.A.
100
N.A.
N.A.
100
100
93.3
86.6
N.A.
100
93.3
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.4
40.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
57.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
86
8
8
8
0
0
0
8
0
0
86
0
0
% C
% Asp:
15
15
8
0
0
0
0
8
0
65
0
0
0
0
15
% D
% Glu:
8
65
0
0
0
72
15
8
0
0
0
8
0
8
58
% E
% Phe:
0
8
0
0
0
0
65
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
36
0
8
0
% K
% Leu:
8
0
0
0
0
0
22
0
86
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
29
0
% N
% Pro:
58
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
15
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
8
43
0
0
0
% R
% Ser:
15
0
0
86
0
0
0
8
0
8
8
0
0
15
15
% S
% Thr:
0
0
0
0
8
0
0
65
0
8
0
0
0
36
8
% T
% Val:
0
0
8
0
79
8
0
0
0
0
65
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _