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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2C
All Species:
35.76
Human Site:
T261
Identified Species:
60.51
UniProt:
P19387
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19387
NP_116558.1
275
31441
T261
K
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
Chimpanzee
Pan troglodytes
XP_510992
242
27800
Q229
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
S
Rhesus Macaque
Macaca mulatta
XP_001098211
257
29446
L244
T
T
W
S
P
V
A
L
C
V
L
K
P
L
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97760
275
31292
T261
K
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511558
352
38872
T338
K
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
Chicken
Gallus gallus
XP_414001
275
31371
T261
K
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
Frog
Xenopus laevis
NP_001084998
275
31317
T261
K
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
Zebra Danio
Brachydanio rerio
NP_956215
275
31337
T261
K
K
L
S
D
L
Q
T
Q
L
S
H
E
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477419
275
31224
T262
N
K
L
S
N
L
Q
T
Q
L
S
H
E
S
Q
Honey Bee
Apis mellifera
XP_624836
276
31595
T261
N
K
L
S
N
L
Q
T
Q
L
S
H
E
V
Q
Nematode Worm
Caenorhab. elegans
NP_492361
282
32359
L267
L
K
R
K
L
E
E
L
N
M
A
L
S
N
E
Sea Urchin
Strong. purpuratus
XP_001176308
275
30823
T259
K
K
L
S
D
L
Q
T
Q
H
S
H
E
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39211
319
35443
S265
E
I
S
P
K
D
D
S
F
I
F
T
V
E
S
Baker's Yeast
Sacchar. cerevisiae
P16370
318
35279
V255
I
D
T
L
Q
K
K
V
A
S
I
L
L
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
77.8
N.A.
N.A.
96.7
N.A.
N.A.
69.5
96.3
93.8
89.8
N.A.
69
69.9
54.9
71.6
Protein Similarity:
100
86.9
81.4
N.A.
N.A.
97
N.A.
N.A.
74.7
99.6
98.1
96.7
N.A.
89
89.8
75.1
86.1
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
80
80
6.6
86.6
P-Site Similarity:
100
6.6
26.6
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
86.6
93.3
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.4
40.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
57.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
8
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
50
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
8
0
0
0
0
8
65
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
65
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
8
8
0
8
43
0
% I
% Lys:
58
72
0
8
8
8
8
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
65
8
15
65
0
15
8
58
8
15
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
15
0
0
0
15
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
8
65
8
65
0
0
0
0
8
65
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
15
72
0
0
0
8
0
15
65
0
8
8
22
% S
% Thr:
8
8
8
0
0
0
8
65
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
8
0
8
0
8
0
0
8
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _