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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2C
All Species:
37.58
Human Site:
Y84
Identified Species:
63.59
UniProt:
P19387
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19387
NP_116558.1
275
31441
Y84
D
I
V
D
K
L
Q
Y
S
R
D
C
T
C
E
Chimpanzee
Pan troglodytes
XP_510992
242
27800
E59
S
R
D
C
T
C
E
E
F
C
P
E
C
S
V
Rhesus Macaque
Macaca mulatta
XP_001098211
257
29446
I74
R
L
G
L
I
P
L
I
S
D
D
I
V
D
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97760
275
31292
Y84
D
I
V
D
K
L
Q
Y
S
R
D
C
T
C
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511558
352
38872
Y161
D
I
V
D
K
L
Q
Y
S
R
D
C
T
C
E
Chicken
Gallus gallus
XP_414001
275
31371
Y84
D
I
V
D
K
M
Q
Y
S
R
D
C
T
C
D
Frog
Xenopus laevis
NP_001084998
275
31317
Y84
D
I
V
D
K
L
Q
Y
S
R
D
C
T
C
D
Zebra Danio
Brachydanio rerio
NP_956215
275
31337
Y84
D
I
V
D
K
M
Q
Y
S
R
D
C
T
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477419
275
31224
Y84
D
V
V
E
R
L
Q
Y
T
R
D
C
I
C
L
Honey Bee
Apis mellifera
XP_624836
276
31595
Y84
D
V
V
D
R
I
Q
Y
T
R
D
C
Q
C
M
Nematode Worm
Caenorhab. elegans
NP_492361
282
32359
Y84
Y
H
V
E
K
M
Q
Y
T
R
D
C
E
C
A
Sea Urchin
Strong. purpuratus
XP_001176308
275
30823
F84
E
V
V
D
K
L
N
F
N
R
D
C
G
C
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39211
319
35443
D89
M
S
M
R
F
S
R
D
C
D
A
C
D
G
D
Baker's Yeast
Sacchar. cerevisiae
P16370
318
35279
Y82
M
D
I
E
Q
L
E
Y
S
R
D
C
F
C
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
77.8
N.A.
N.A.
96.7
N.A.
N.A.
69.5
96.3
93.8
89.8
N.A.
69
69.9
54.9
71.6
Protein Similarity:
100
86.9
81.4
N.A.
N.A.
97
N.A.
N.A.
74.7
99.6
98.1
96.7
N.A.
89
89.8
75.1
86.1
P-Site Identity:
100
0
13.3
N.A.
N.A.
100
N.A.
N.A.
100
86.6
93.3
86.6
N.A.
60
60
53.3
60
P-Site Similarity:
100
6.6
26.6
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
86.6
86.6
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.4
40.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.3
57.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
8
0
8
0
0
8
8
0
86
8
79
0
% C
% Asp:
58
8
8
58
0
0
0
8
0
15
86
0
8
8
29
% D
% Glu:
8
0
0
22
0
0
15
8
0
0
0
8
8
0
36
% E
% Phe:
0
0
0
0
8
0
0
8
8
0
0
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
43
8
0
8
8
0
8
0
0
0
8
8
0
0
% I
% Lys:
0
0
0
0
58
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
8
0
50
8
0
0
0
0
0
0
0
8
% L
% Met:
15
0
8
0
0
22
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
65
0
0
0
0
0
8
0
0
% Q
% Arg:
8
8
0
8
15
0
8
0
0
79
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
8
0
0
58
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
8
0
0
0
22
0
0
0
43
0
0
% T
% Val:
0
22
72
0
0
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _