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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD53 All Species: 18.18
Human Site: S127 Identified Species: 44.44
UniProt: P19397 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19397 NP_000551.1 219 24341 S127 D S I H R Y H S D N S T K A A
Chimpanzee Pan troglodytes XP_001162778 199 22213 Q108 I L L F V Y E Q K L N E Y V A
Rhesus Macaque Macaca mulatta XP_001102109 219 24281 S127 D S I H R Y H S D N S T K A A
Dog Lupus familis XP_852492 215 23995 L123 D S I K Q Y H L D N S T R A T
Cat Felis silvestris
Mouse Mus musculus Q61451 219 24145 S127 D S I Q H Y H S D N S T M K A
Rat Rattus norvegicus P24485 219 24149 S127 D S I Q H Y H S D N S T R M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512431 219 24622 K127 D S F Q H Y H K D N A T K N A
Chicken Gallus gallus XP_421038 266 29641 T156 K G L H L Y G T D G N I G L T
Frog Xenopus laevis Q6DCQ3 239 26764 S128 D G L L L Y N S E N N V G L K
Zebra Danio Brachydanio rerio Q6GMK6 239 26765 T128 D G L R L Y N T D N N V G L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 97.7 84.9 N.A. 83.1 81.2 N.A. 67.1 36 42.6 41.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.4 98.1 90.4 N.A. 89.9 89.9 N.A. 80.8 56 61.5 61.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 66.6 N.A. 73.3 73.3 N.A. 60 20 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 80 N.A. 73.3 80 N.A. 66.6 40 53.3 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 30 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 80 0 0 0 0 0 0 0 80 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 10 0 0 10 0 0 0 % E
% Phe: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 30 0 0 0 0 10 0 0 10 0 0 30 0 0 % G
% His: 0 0 0 30 30 0 60 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 50 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 10 0 0 10 0 0 0 10 10 0 0 0 30 10 10 % K
% Leu: 0 10 40 10 30 0 0 10 0 10 0 0 0 30 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 0 0 0 0 0 20 0 0 80 40 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 30 10 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 20 0 0 0 0 0 0 0 20 0 10 % R
% Ser: 0 60 0 0 0 0 0 50 0 0 50 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 0 60 0 0 20 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 20 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 100 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _