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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD53
All Species:
8.48
Human Site:
S137
Identified Species:
20.74
UniProt:
P19397
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19397
NP_000551.1
219
24341
S137
S
T
K
A
A
W
D
S
I
Q
S
F
L
Q
C
Chimpanzee
Pan troglodytes
XP_001162778
199
22213
L118
N
E
Y
V
A
K
G
L
T
D
S
I
H
R
Y
Rhesus Macaque
Macaca mulatta
XP_001102109
219
24281
S137
S
T
K
A
A
W
D
S
I
Q
S
F
L
Q
C
Dog
Lupus familis
XP_852492
215
23995
S133
S
T
R
A
T
W
D
S
I
Q
S
V
L
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q61451
219
24145
F137
S
T
M
K
A
W
D
F
I
Q
T
Q
L
Q
C
Rat
Rattus norvegicus
P24485
219
24149
F137
S
T
R
M
A
W
D
F
I
Q
S
Q
L
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512431
219
24622
A137
A
T
K
N
A
W
D
A
V
Q
Q
Q
L
Q
C
Chicken
Gallus gallus
XP_421038
266
29641
W166
N
I
G
L
T
N
A
W
S
I
I
Q
T
D
F
Frog
Xenopus laevis
Q6DCQ3
239
26764
W138
N
V
G
L
K
N
A
W
N
I
I
Q
A
E
M
Zebra Danio
Brachydanio rerio
Q6GMK6
239
26765
W138
N
V
G
L
R
N
A
W
N
I
I
Q
A
E
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
97.7
84.9
N.A.
83.1
81.2
N.A.
67.1
36
42.6
41.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.4
98.1
90.4
N.A.
89.9
89.9
N.A.
80.8
56
61.5
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
80
N.A.
66.6
73.3
N.A.
60
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
86.6
N.A.
73.3
80
N.A.
80
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
30
60
0
30
10
0
0
0
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% C
% Asp:
0
0
0
0
0
0
60
0
0
10
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
20
0
0
10
% F
% Gly:
0
0
30
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
50
30
30
10
0
0
0
% I
% Lys:
0
0
30
10
10
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
30
0
0
0
10
0
0
0
0
60
0
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
40
0
0
10
0
30
0
0
20
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
60
10
60
0
60
0
% Q
% Arg:
0
0
20
0
10
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
50
0
0
0
0
0
0
30
10
0
50
0
0
0
0
% S
% Thr:
0
60
0
0
20
0
0
0
10
0
10
0
10
0
0
% T
% Val:
0
20
0
10
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
60
0
30
0
0
0
0
0
0
10
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _