Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNNI3 All Species: 16.06
Human Site: T119 Identified Species: 35.33
UniProt: P19429 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19429 NP_000354.4 210 24008 T119 Y D I E A K V T K N I T E I A
Chimpanzee Pan troglodytes XP_001134934 215 23988 Q126 G L G F A E L Q D L C R Q L H
Rhesus Macaque Macaca mulatta XP_001085820 210 23930 T119 Y D I Q A K V T K N I T E I A
Dog Lupus familis XP_851068 182 21393 Q87 Y D M E V R V Q K S T K E L E
Cat Felis silvestris
Mouse Mus musculus P48787 211 24240 T120 Y D V E A K V T K N I T E I A
Rat Rattus norvegicus P23693 211 24141 T120 Y D V E A K V T K N I T E I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P68246 183 21216 Q87 Y D T E V K L Q K T N K E L E
Frog Xenopus laevis P50754 244 28179 N144 Y D M E A K V N K N I T E L E
Zebra Danio Brachydanio rerio NP_001008613 182 21013 L88 Y D I E A K V L H N T R E I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P36188 269 30063 R179 W D L E Y E V R K K D W E I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9GYF1 242 27542 S121 Y D I N Y V V S Q T E A E I N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 98 53.8 N.A. 92.4 92.4 N.A. N.A. 53.3 63.1 54.7 N.A. 29 N.A. 22.7 N.A.
Protein Similarity: 100 84.6 98.5 68.5 N.A. 95.2 95.2 N.A. N.A. 69 74.1 70 N.A. 46.4 N.A. 47.9 N.A.
P-Site Identity: 100 6.6 93.3 40 N.A. 93.3 93.3 N.A. N.A. 40 73.3 66.6 N.A. 40 N.A. 40 N.A.
P-Site Similarity: 100 33.3 100 66.6 N.A. 100 100 N.A. N.A. 53.3 86.6 66.6 N.A. 60 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 64 0 0 0 0 0 0 10 0 0 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 91 0 0 0 0 0 0 10 0 10 0 0 0 0 % D
% Glu: 0 0 0 73 0 19 0 0 0 0 10 0 91 0 28 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % H
% Ile: 0 0 37 0 0 0 0 0 0 0 46 0 0 64 0 % I
% Lys: 0 0 0 0 0 64 0 0 73 10 0 19 0 0 10 % K
% Leu: 0 10 10 0 0 0 19 10 0 10 0 0 0 37 0 % L
% Met: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 10 0 55 10 0 0 0 19 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 28 10 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 10 0 10 0 0 0 19 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 0 0 37 0 19 19 46 0 0 0 % T
% Val: 0 0 19 0 19 10 82 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 82 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _