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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC3 All Species: 29.7
Human Site: S763 Identified Species: 50.26
UniProt: P19447 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19447 NP_000113.1 782 89278 S763 T V Y M E Y H S S R S K A P S
Chimpanzee Pan troglodytes XP_525907 797 91016 S778 T V Y M E Y H S S R S K A P S
Rhesus Macaque Macaca mulatta XP_001086722 782 89213 S763 T V Y M E Y H S S R S K A P S
Dog Lupus familis XP_533314 782 89111 S763 T V Y M E Y H S A R S K A S T
Cat Felis silvestris
Mouse Mus musculus P49135 783 89108 S764 T V Y M E Y H S S R S K A S S
Rat Rattus norvegicus Q4G005 782 89081 S763 T V Y M E Y H S S R N K A S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKK7 788 89662 S760 A V Y M E Y H S S R S K A S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7ZVV1 782 89269 P762 L Y M E Y Q M P R G S K A S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02870 798 90330 Y779 G G D D A I Y Y E H R K K N I
Honey Bee Apis mellifera XP_624125 795 91356 P779 Y Y E Y K K A P S S S T A N K
Nematode Worm Caenorhab. elegans NP_499487 789 89492 K775 A Q Y H S K A K A I A E R H P
Sea Urchin Strong. purpuratus XP_794167 745 84913 E731 A T D A D A E E E I V P G D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FUG4 766 86717 S739 R V Y M E Y N S G R Q K S G N
Baker's Yeast Sacchar. cerevisiae Q00578 843 95322 G809 G S L S G L A G G E D M A Y M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 99.7 97 N.A. 95.7 95.9 N.A. N.A. 89.9 N.A. 88.6 N.A. 68.5 69.4 63.3 69.9
Protein Similarity: 100 93.5 99.7 98.7 N.A. 97.4 97.6 N.A. N.A. 94.6 N.A. 94.6 N.A. 80.8 82.7 77.1 82.4
P-Site Identity: 100 100 100 80 N.A. 93.3 80 N.A. N.A. 86.6 N.A. 20 N.A. 6.6 20 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 20 N.A. 13.3 26.6 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 54.8 50.6 N.A.
Protein Similarity: N.A. N.A. N.A. 70.8 68.2 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 8 8 8 22 0 15 0 8 0 72 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 8 8 0 0 0 0 0 8 0 0 8 0 % D
% Glu: 0 0 8 8 58 0 8 8 15 8 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 8 0 0 8 0 0 8 15 8 0 0 8 8 0 % G
% His: 0 0 0 8 0 0 50 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 15 0 0 0 0 8 % I
% Lys: 0 0 0 0 8 15 0 8 0 0 0 72 8 0 8 % K
% Leu: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 8 58 0 0 8 0 0 0 0 8 0 0 8 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 8 0 0 15 8 % N
% Pro: 0 0 0 0 0 0 0 15 0 0 0 8 0 22 8 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 8 58 8 0 8 0 0 % R
% Ser: 0 8 0 8 8 0 0 58 50 8 58 0 8 36 36 % S
% Thr: 43 8 0 0 0 0 0 0 0 0 0 8 0 0 15 % T
% Val: 0 58 0 0 0 0 0 0 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 15 65 8 8 58 8 8 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _