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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC3
All Species:
23.33
Human Site:
S766
Identified Species:
39.49
UniProt:
P19447
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19447
NP_000113.1
782
89278
S766
M
E
Y
H
S
S
R
S
K
A
P
S
K
H
V
Chimpanzee
Pan troglodytes
XP_525907
797
91016
S781
M
E
Y
H
S
S
R
S
K
A
P
S
K
H
V
Rhesus Macaque
Macaca mulatta
XP_001086722
782
89213
S766
M
E
Y
H
S
S
R
S
K
A
P
S
K
H
V
Dog
Lupus familis
XP_533314
782
89111
S766
M
E
Y
H
S
A
R
S
K
A
S
T
K
H
V
Cat
Felis silvestris
Mouse
Mus musculus
P49135
783
89108
S767
M
E
Y
H
S
S
R
S
K
A
S
S
K
H
V
Rat
Rattus norvegicus
Q4G005
782
89081
N766
M
E
Y
H
S
S
R
N
K
A
S
T
K
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKK7
788
89662
S763
M
E
Y
H
S
S
R
S
K
A
S
S
N
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZVV1
782
89269
S765
E
Y
Q
M
P
R
G
S
K
A
S
V
G
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02870
798
90330
R782
D
A
I
Y
Y
E
H
R
K
K
N
I
G
S
V
Honey Bee
Apis mellifera
XP_624125
795
91356
S782
Y
K
K
A
P
S
S
S
T
A
N
K
H
P
L
Nematode Worm
Caenorhab. elegans
NP_499487
789
89492
A778
H
S
K
A
K
A
I
A
E
R
H
P
L
F
K
Sea Urchin
Strong. purpuratus
XP_794167
745
84913
V734
A
D
A
E
E
E
I
V
P
G
D
L
K
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FUG4
766
86717
Q742
M
E
Y
N
S
G
R
Q
K
S
G
N
Q
S
K
Baker's Yeast
Sacchar. cerevisiae
Q00578
843
95322
D812
S
G
L
A
G
G
E
D
M
A
Y
M
E
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.7
97
N.A.
95.7
95.9
N.A.
N.A.
89.9
N.A.
88.6
N.A.
68.5
69.4
63.3
69.9
Protein Similarity:
100
93.5
99.7
98.7
N.A.
97.4
97.6
N.A.
N.A.
94.6
N.A.
94.6
N.A.
80.8
82.7
77.1
82.4
P-Site Identity:
100
100
100
80
N.A.
93.3
80
N.A.
N.A.
73.3
N.A.
20
N.A.
13.3
20
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
20
N.A.
20
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.8
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
22
0
15
0
8
0
72
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
8
58
0
8
8
15
8
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
8
15
8
0
0
8
8
0
15
0
8
% G
% His:
8
0
0
50
0
0
8
0
0
0
8
0
8
43
8
% H
% Ile:
0
0
8
0
0
0
15
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
15
0
8
0
0
0
72
8
0
8
50
15
15
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
8
% L
% Met:
58
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
15
8
8
0
8
% N
% Pro:
0
0
0
0
15
0
0
0
8
0
22
8
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
58
8
0
8
0
0
0
0
0
% R
% Ser:
8
8
0
0
58
50
8
58
0
8
36
36
0
15
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
15
0
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
58
8
8
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _