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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM21
All Species:
8.48
Human Site:
S41
Identified Species:
31.11
UniProt:
P19474
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19474
NP_003132.2
475
54170
S41
S
F
C
Q
E
C
I
S
Q
V
G
K
G
G
G
Chimpanzee
Pan troglodytes
Q5D7J1
493
56253
K45
C
L
T
A
N
H
K
K
S
M
L
D
K
G
E
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
Y49
N
H
K
K
S
M
L
Y
K
E
G
E
R
S
C
Dog
Lupus familis
XP_542344
458
52197
S41
S
F
C
H
K
C
I
S
E
V
G
K
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62191
470
54156
F45
C
F
C
K
E
C
I
F
E
V
G
K
N
G
G
Rat
Rattus norvegicus
Q6MFZ5
488
56376
T54
N
F
C
K
A
C
I
T
R
W
W
E
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509541
527
60558
A99
N
F
C
R
S
C
I
A
R
C
W
E
D
Q
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.3
42.2
73.4
N.A.
68.2
41.1
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.6
58.3
81.4
N.A.
81.8
59.4
N.A.
55.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
73.3
N.A.
66.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
40
86.6
N.A.
80
60
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
15
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
29
0
72
0
0
72
0
0
0
15
0
0
0
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
15
43
0
0
% D
% Glu:
0
0
0
0
29
0
0
0
29
15
0
43
0
0
43
% E
% Phe:
0
72
0
0
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
58
0
15
58
43
% G
% His:
0
15
0
15
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
43
15
0
15
15
15
0
0
43
15
0
0
% K
% Leu:
0
15
0
0
0
0
15
0
0
0
15
0
0
15
0
% L
% Met:
0
0
0
0
0
15
0
0
0
15
0
0
0
0
0
% M
% Asn:
43
0
0
0
15
0
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
15
0
0
0
0
15
0
% Q
% Arg:
0
0
0
15
0
0
0
0
29
0
0
0
15
0
0
% R
% Ser:
29
0
0
0
29
0
0
29
15
0
0
0
0
15
0
% S
% Thr:
0
0
15
0
0
0
0
15
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
15
29
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _