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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFE3
All Species:
20
Human Site:
S274
Identified Species:
62.86
UniProt:
P19532
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19532
NP_006512.2
575
61521
S274
E
I
I
S
L
E
S
S
Y
N
D
E
M
L
S
Chimpanzee
Pan troglodytes
A2T713
347
38902
Y98
S
G
S
I
L
D
V
Y
S
G
E
Q
G
I
S
Rhesus Macaque
Macaca mulatta
XP_001105073
575
61529
S274
E
I
I
S
L
E
S
S
Y
N
D
E
M
L
S
Dog
Lupus familis
XP_851347
571
61083
S271
E
I
I
S
L
E
S
S
Y
N
D
E
M
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64092
572
61518
S273
E
I
I
S
L
E
S
S
Y
N
D
E
M
L
S
Rat
Rattus norvegicus
Q63302
317
35156
V68
L
S
G
S
I
L
D
V
Y
S
G
E
Q
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507724
879
92892
S604
E
I
I
S
L
E
S
S
Y
N
D
E
I
L
N
Chicken
Gallus gallus
Q5XFQ6
377
42496
I128
Q
R
T
S
I
L
D
I
Y
N
S
D
Q
G
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.3
99.4
96.3
N.A.
95.8
31.8
N.A.
43.9
34
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43.4
99.4
96.8
N.A.
97.3
39.6
N.A.
50.2
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
20
N.A.
86.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
33.3
N.A.
100
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
25
0
0
0
63
13
0
0
0
% D
% Glu:
63
0
0
0
0
63
0
0
0
0
13
75
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
13
0
0
0
0
0
0
13
13
0
13
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
63
63
13
25
0
0
13
0
0
0
0
13
13
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
0
0
0
75
25
0
0
0
0
0
0
0
63
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
13
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
13
25
0
0
% Q
% Arg:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
13
13
88
0
0
63
63
13
13
13
0
0
0
63
% S
% Thr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
88
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _