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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WT1 All Species: 18.18
Human Site: S395 Identified Species: 50
UniProt: P19544 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19544 NP_000369.3 449 49188 S395 C Q R K F S R S D H L K T H T
Chimpanzee Pan troglodytes XP_001138640 498 54786 F444 C K T C Q R K F S R S D H L K
Rhesus Macaque Macaca mulatta XP_001084704 689 74227 F635 C K T C Q R K F S R S D H L K
Dog Lupus familis XP_851572 930 99262 F876 C K T C Q R K F S R S D H L K
Cat Felis silvestris
Mouse Mus musculus P22561 449 49228 S395 C Q R K F S R S D H L K T H T
Rat Rattus norvegicus P49952 448 49175 S394 C Q R K F S R S D H L K T H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990547 417 46939 S363 C Q R K F S R S D H L K T H T
Frog Xenopus laevis Q08427 421 46362 H368 R K R H T K I H L R Q K E R K
Zebra Danio Brachydanio rerio NP_571121 419 46907 S365 C Q R K F S R S D H L K T H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.9 64.4 45.5 N.A. 96.4 96.8 N.A. N.A. 84.4 20 73 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 79.7 64.5 46.6 N.A. 97.3 98 N.A. N.A. 88.1 32.7 79.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 100 100 N.A. N.A. 100 13.3 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 20 N.A. 100 100 N.A. N.A. 100 20 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 89 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 56 0 0 34 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 56 0 0 34 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 12 0 0 0 12 0 56 0 0 34 56 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % I
% Lys: 0 45 0 56 0 12 34 0 0 0 0 67 0 0 45 % K
% Leu: 0 0 0 0 0 0 0 0 12 0 56 0 0 34 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 56 0 0 34 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 12 0 67 0 0 34 56 0 0 45 0 0 0 12 0 % R
% Ser: 0 0 0 0 0 56 0 56 34 0 34 0 0 0 0 % S
% Thr: 0 0 34 0 12 0 0 0 0 0 0 0 56 0 56 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _