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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WT1
All Species:
22.73
Human Site:
T219
Identified Species:
62.5
UniProt:
P19544
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19544
NP_000369.3
449
49188
T219
S
Q
A
L
L
L
R
T
P
Y
S
S
D
N
L
Chimpanzee
Pan troglodytes
XP_001138640
498
54786
T271
S
Q
A
L
L
L
R
T
P
Y
S
S
D
N
L
Rhesus Macaque
Macaca mulatta
XP_001084704
689
74227
T462
S
Q
A
L
L
L
R
T
P
Y
S
S
D
N
L
Dog
Lupus familis
XP_851572
930
99262
T703
S
Q
A
L
L
L
R
T
P
Y
S
S
D
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P22561
449
49228
T219
S
Q
A
L
L
L
R
T
P
Y
S
S
D
N
L
Rat
Rattus norvegicus
P49952
448
49175
T218
S
Q
A
L
L
L
R
T
P
Y
S
S
D
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990547
417
46939
D190
Y
G
C
H
T
P
T
D
T
C
T
G
S
Q
A
Frog
Xenopus laevis
Q08427
421
46362
G196
P
S
Y
P
S
P
K
G
A
S
D
G
G
M
F
Zebra Danio
Brachydanio rerio
NP_571121
419
46907
P190
P
V
Y
G
C
H
T
P
S
D
S
C
T
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.9
64.4
45.5
N.A.
96.4
96.8
N.A.
N.A.
84.4
20
73
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.7
64.5
46.6
N.A.
97.3
98
N.A.
N.A.
88.1
32.7
79.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
0
0
0
0
12
0
0
0
0
0
12
% A
% Cys:
0
0
12
0
12
0
0
0
0
12
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
12
12
0
67
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
0
12
0
0
0
12
0
0
0
23
12
12
0
% G
% His:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
67
67
67
0
0
0
0
0
0
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% N
% Pro:
23
0
0
12
0
23
0
12
67
0
0
0
0
0
0
% P
% Gln:
0
67
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% R
% Ser:
67
12
0
0
12
0
0
0
12
12
78
67
12
0
12
% S
% Thr:
0
0
0
0
12
0
23
67
12
0
12
0
12
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
23
0
0
0
0
0
0
67
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _