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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WT1 All Species: 18.79
Human Site: Y109 Identified Species: 51.67
UniProt: P19544 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19544 NP_000369.3 449 49188 Y109 G T A G A C R Y G P F G P P P
Chimpanzee Pan troglodytes XP_001138640 498 54786 Y161 G T A G A C R Y G P F G P P P
Rhesus Macaque Macaca mulatta XP_001084704 689 74227 Y352 G T A G A C R Y G P F G P P P
Dog Lupus familis XP_851572 930 99262 G593 G A S G A A R G A V G T R P L
Cat Felis silvestris
Mouse Mus musculus P22561 449 49228 Y109 G T A G A C R Y G P F G P P P
Rat Rattus norvegicus P49952 448 49175 Y108 G T A G A C R Y G P F G P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990547 417 46939 S80 S A F T V H F S G Q F T G T A
Frog Xenopus laevis Q08427 421 46362 Q86 Y P L A P R T Q P I A Y M G K
Zebra Danio Brachydanio rerio NP_571121 419 46907 V80 C G L S A F T V H F S G Q F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.9 64.4 45.5 N.A. 96.4 96.8 N.A. N.A. 84.4 20 73 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 79.7 64.5 46.6 N.A. 97.3 98 N.A. N.A. 88.1 32.7 79.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 33.3 N.A. 100 100 N.A. N.A. 13.3 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 100 100 N.A. N.A. 13.3 0 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 56 12 78 12 0 0 12 0 12 0 0 0 12 % A
% Cys: 12 0 0 0 0 56 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 0 0 12 12 0 0 12 67 0 0 12 0 % F
% Gly: 67 12 0 67 0 0 0 12 67 0 12 67 12 12 0 % G
% His: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 12 0 0 0 12 56 0 0 56 67 56 % P
% Gln: 0 0 0 0 0 0 0 12 0 12 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 12 67 0 0 0 0 0 12 0 0 % R
% Ser: 12 0 12 12 0 0 0 12 0 0 12 0 0 0 0 % S
% Thr: 0 56 0 12 0 0 23 0 0 0 0 23 0 12 12 % T
% Val: 0 0 0 0 12 0 0 12 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 56 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _