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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EN2
All Species:
4.24
Human Site:
S23
Identified Species:
7.78
UniProt:
P19622
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19622
NP_001418.2
333
34211
S23
E
G
Q
R
Q
P
E
S
S
P
G
G
G
S
G
Chimpanzee
Pan troglodytes
XP_001146034
399
41238
A24
C
L
Q
E
E
C
P
A
S
L
N
R
E
A
T
Rhesus Macaque
Macaca mulatta
XP_001106130
334
34311
S24
G
Q
R
Q
P
E
S
S
P
G
G
G
S
G
G
Dog
Lupus familis
XP_854121
247
25817
Cat
Felis silvestris
Mouse
Mus musculus
P09066
324
33799
P19
A
A
E
A
Q
R
Q
P
E
P
S
S
G
G
G
Rat
Rattus norvegicus
NP_001102684
323
33670
P19
A
A
E
A
Q
R
Q
P
E
P
S
P
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512614
188
20519
Chicken
Gallus gallus
Q05917
288
30431
R9
E
E
G
G
R
S
P
R
E
E
A
A
E
P
Q
Frog
Xenopus laevis
P52729
265
29878
Zebra Danio
Brachydanio rerio
P31533
261
29466
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02836
552
59392
S11
E
D
R
C
S
P
Q
S
A
P
S
P
I
T
L
Honey Bee
Apis mellifera
P09076
109
12608
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794753
249
28228
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.1
98.1
46.2
N.A.
86.7
86.7
N.A.
48.9
66
57.3
56.1
N.A.
27.5
22.8
N.A.
38.7
Protein Similarity:
100
75.1
99
50.7
N.A.
87.9
88.5
N.A.
52.2
70.5
64.8
63.3
N.A.
37.3
27.3
N.A.
51.3
P-Site Identity:
100
13.3
26.6
0
N.A.
26.6
26.6
N.A.
0
6.6
0
0
N.A.
26.6
0
N.A.
0
P-Site Similarity:
100
33.3
40
0
N.A.
40
40
N.A.
0
13.3
0
0
N.A.
53.3
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
0
16
0
0
0
8
8
0
8
8
0
8
0
% A
% Cys:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
8
16
8
8
8
8
0
24
8
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
8
0
0
0
0
0
8
16
16
24
24
31
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
16
16
16
8
31
0
16
0
8
0
% P
% Gln:
0
8
16
8
24
0
24
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
16
8
8
16
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
8
8
8
24
16
0
24
8
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _