KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EN2
All Species:
22.73
Human Site:
S282
Identified Species:
41.67
UniProt:
P19622
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19622
NP_001418.2
333
34211
S282
Q
S
L
A
Q
E
L
S
L
N
E
S
Q
I
K
Chimpanzee
Pan troglodytes
XP_001146034
399
41238
S348
Q
S
L
A
Q
E
L
S
L
N
E
S
Q
I
K
Rhesus Macaque
Macaca mulatta
XP_001106130
334
34311
S283
Q
S
L
A
Q
E
L
S
L
N
E
S
Q
I
K
Dog
Lupus familis
XP_854121
247
25817
E199
A
Q
E
L
S
L
N
E
S
Q
I
K
I
W
F
Cat
Felis silvestris
Mouse
Mus musculus
P09066
324
33799
S273
Q
S
L
A
Q
E
L
S
L
N
E
S
Q
I
K
Rat
Rattus norvegicus
NP_001102684
323
33670
S272
Q
S
L
A
Q
E
L
S
L
N
E
S
Q
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512614
188
20519
E140
A
Q
E
L
S
L
N
E
S
Q
I
K
I
W
F
Chicken
Gallus gallus
Q05917
288
30431
G237
Q
S
L
A
Q
E
L
G
L
N
E
S
Q
I
K
Frog
Xenopus laevis
P52729
265
29878
S214
Q
S
L
A
Q
E
L
S
L
N
E
S
Q
I
K
Zebra Danio
Brachydanio rerio
P31533
261
29466
E213
A
Q
E
L
G
L
N
E
S
Q
I
K
I
W
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02836
552
59392
G492
Q
Q
L
S
S
E
L
G
L
N
E
A
Q
I
K
Honey Bee
Apis mellifera
P09076
109
12608
E61
S
R
D
L
G
L
T
E
A
Q
I
K
I
W
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794753
249
28228
A201
T
G
L
K
N
G
L
A
R
Q
L
M
A
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.1
98.1
46.2
N.A.
86.7
86.7
N.A.
48.9
66
57.3
56.1
N.A.
27.5
22.8
N.A.
38.7
Protein Similarity:
100
75.1
99
50.7
N.A.
87.9
88.5
N.A.
52.2
70.5
64.8
63.3
N.A.
37.3
27.3
N.A.
51.3
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
93.3
100
0
N.A.
66.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
0
N.A.
100
100
N.A.
0
93.3
100
0
N.A.
80
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
54
0
0
0
8
8
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
24
0
0
62
0
31
0
0
62
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% F
% Gly:
0
8
0
0
16
8
0
16
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
31
0
31
62
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
31
0
0
62
% K
% Leu:
0
0
70
31
0
31
70
0
62
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
24
0
0
62
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
62
31
0
0
54
0
0
0
0
39
0
0
62
8
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
54
0
8
24
0
0
47
24
0
0
54
0
0
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _