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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRM All Species: 35.15
Human Site: S183 Identified Species: 64.44
UniProt: P19623 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19623 NP_003123.2 302 33825 S183 D P M G P A E S L F K E S Y Y
Chimpanzee Pan troglodytes XP_514381 302 33806 S183 D P M G P A E S L F K E S Y Y
Rhesus Macaque Macaca mulatta XP_001102838 302 33815 S183 D P M G P A E S L F K E S Y Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64674 302 33976 S183 D P M G P A E S L F K E S Y Y
Rat Rattus norvegicus NP_445916 302 33978 S183 D P M G P A E S L F K E S Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234728 243 27438 C147 R E D G I L C C Q G E C Q W L
Frog Xenopus laevis NP_001084875 290 32833 S172 D P V G P A E S L F K E S Y Y
Zebra Danio Brachydanio rerio NP_957328 289 32822 S171 D P V G P A E S L F K E S Y Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120306 293 32592 C171 D P V G P A E C L F Q E S Y F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796573 284 31888 M171 D P V G P A E M L F E K E Y F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZUB3 334 36535 E211 D P I G P A K E L F E K P F F
Baker's Yeast Sacchar. cerevisiae Q12074 293 33306 T178 D P E G P A E T L F Q K E Y F
Red Bread Mold Neurospora crassa Q9Y8H7 291 33056 S176 D P E G P A E S L F Q K P Y F
Conservation
Percent
Protein Identity: 100 99.6 99.6 N.A. N.A. 94.6 95.3 N.A. N.A. 66.2 82.7 76.1 N.A. N.A. 57.6 N.A. 64.2
Protein Similarity: 100 100 99.6 N.A. N.A. 97.6 98 N.A. N.A. 73.8 91.7 88.7 N.A. N.A. 74.1 N.A. 81.1
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 6.6 93.3 93.3 N.A. N.A. 73.3 N.A. 60
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 20 100 100 N.A. N.A. 93.3 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 47 54.9 57.2
Protein Similarity: N.A. N.A. N.A. 65.8 76.1 78.4
P-Site Identity: N.A. N.A. N.A. 46.6 60 66.6
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 16 0 0 0 8 0 0 0 % C
% Asp: 93 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 16 0 0 0 85 8 0 0 24 62 16 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 93 0 0 0 8 39 % F
% Gly: 0 0 0 100 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 54 31 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 0 93 0 0 0 0 0 8 % L
% Met: 0 0 39 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 93 0 0 93 0 0 0 0 0 0 0 16 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 24 0 8 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 62 0 0 0 0 62 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 85 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _