KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRM
All Species:
43.64
Human Site:
T172
Identified Species:
80
UniProt:
P19623
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19623
NP_003123.2
302
33825
T172
D
A
F
D
V
I
I
T
D
S
S
D
P
M
G
Chimpanzee
Pan troglodytes
XP_514381
302
33806
T172
D
A
F
D
V
I
I
T
D
S
S
D
P
M
G
Rhesus Macaque
Macaca mulatta
XP_001102838
302
33815
T172
D
A
F
D
V
I
I
T
D
S
S
D
P
M
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64674
302
33976
T172
D
A
F
D
V
I
I
T
D
S
S
D
P
M
G
Rat
Rattus norvegicus
NP_445916
302
33978
T172
D
A
F
D
V
I
I
T
D
S
S
D
P
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234728
243
27438
K136
E
S
Y
Y
Q
L
M
K
T
A
L
R
E
D
G
Frog
Xenopus laevis
NP_001084875
290
32833
T161
D
A
F
D
I
I
I
T
D
S
S
D
P
V
G
Zebra Danio
Brachydanio rerio
NP_957328
289
32822
T160
D
A
F
D
I
I
I
T
D
S
S
D
P
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120306
293
32592
T160
G
Q
F
D
V
I
I
T
D
S
S
D
P
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796573
284
31888
T160
N
A
F
D
V
I
I
T
D
S
S
D
P
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZUB3
334
36535
V200
G
S
Y
D
A
V
I
V
D
S
S
D
P
I
G
Baker's Yeast
Sacchar. cerevisiae
Q12074
293
33306
T167
N
T
F
D
V
I
I
T
D
S
S
D
P
E
G
Red Bread Mold
Neurospora crassa
Q9Y8H7
291
33056
T165
N
T
F
D
V
I
I
T
D
S
S
D
P
E
G
Conservation
Percent
Protein Identity:
100
99.6
99.6
N.A.
N.A.
94.6
95.3
N.A.
N.A.
66.2
82.7
76.1
N.A.
N.A.
57.6
N.A.
64.2
Protein Similarity:
100
100
99.6
N.A.
N.A.
97.6
98
N.A.
N.A.
73.8
91.7
88.7
N.A.
N.A.
74.1
N.A.
81.1
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
6.6
86.6
86.6
N.A.
N.A.
80
N.A.
86.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
46.6
100
100
N.A.
N.A.
86.6
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
47
54.9
57.2
Protein Similarity:
N.A.
N.A.
N.A.
65.8
76.1
78.4
P-Site Identity:
N.A.
N.A.
N.A.
53.3
80
80
P-Site Similarity:
N.A.
N.A.
N.A.
80
86.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
0
0
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
93
0
0
0
0
93
0
0
93
0
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
8
16
0
% E
% Phe:
0
0
85
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
85
93
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
39
0
% M
% Asn:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
16
0
0
0
0
0
0
0
93
93
0
0
0
0
% S
% Thr:
0
16
0
0
0
0
0
85
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
70
8
0
8
0
0
0
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _