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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRM All Species: 33.03
Human Site: T257 Identified Species: 60.56
UniProt: P19623 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19623 NP_003123.2 302 33825 T257 L C S K N P S T N F Q E P V Q
Chimpanzee Pan troglodytes XP_514381 302 33806 T257 L C S K N P S T N F Q E P V Q
Rhesus Macaque Macaca mulatta XP_001102838 302 33815 T257 L C S K N P S T N F Q E P V Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64674 302 33976 T257 L C S K N P S T N F R E P V Q
Rat Rattus norvegicus NP_445916 302 33978 T257 L C S K N P S T N F R E P V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234728 243 27438 V205 N T N F R E P V Q Q L S Q Q Q
Frog Xenopus laevis NP_001084875 290 32833 T246 L C S K N P S T N F K E P V Q
Zebra Danio Brachydanio rerio NP_957328 289 32822 T245 L C S K N S K T N F R E P L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120306 293 32592 T245 L G G L N P E T N F K E P T K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796573 284 31888 T245 L C S T S S D T D F R D P V H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZUB3 334 36535 D286 L C S T E G P D V D F K H P L
Baker's Yeast Sacchar. cerevisiae Q12074 293 33306 C252 V C S K D K T C N V K K P L R
Red Bread Mold Neurospora crassa Q9Y8H7 291 33056 A250 V C S K D P N A N V K V P L R
Conservation
Percent
Protein Identity: 100 99.6 99.6 N.A. N.A. 94.6 95.3 N.A. N.A. 66.2 82.7 76.1 N.A. N.A. 57.6 N.A. 64.2
Protein Similarity: 100 100 99.6 N.A. N.A. 97.6 98 N.A. N.A. 73.8 91.7 88.7 N.A. N.A. 74.1 N.A. 81.1
P-Site Identity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. N.A. 6.6 93.3 66.6 N.A. N.A. 53.3 N.A. 46.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 13.3 100 86.6 N.A. N.A. 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 47 54.9 57.2
Protein Similarity: N.A. N.A. N.A. 65.8 76.1 78.4
P-Site Identity: N.A. N.A. N.A. 20 33.3 40
P-Site Similarity: N.A. N.A. N.A. 26.6 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 85 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 16 0 8 8 8 8 0 8 0 0 0 % D
% Glu: 0 0 0 0 8 8 8 0 0 0 0 62 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 70 8 0 0 0 0 % F
% Gly: 0 8 8 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 70 0 8 8 0 0 0 31 16 0 0 8 % K
% Leu: 77 0 0 8 0 0 0 0 0 0 8 0 0 24 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 62 0 8 0 77 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 62 16 0 0 0 0 0 85 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 24 0 8 8 54 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 31 0 0 0 24 % R
% Ser: 0 0 85 0 8 16 47 0 0 0 0 8 0 0 0 % S
% Thr: 0 8 0 16 0 0 8 70 0 0 0 0 0 8 0 % T
% Val: 16 0 0 0 0 0 0 8 8 16 0 8 0 54 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _