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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRM All Species: 23.94
Human Site: T72 Identified Species: 43.89
UniProt: P19623 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19623 NP_003123.2 302 33825 T72 L D G V I Q C T E R D E F S Y
Chimpanzee Pan troglodytes XP_514381 302 33806 T72 L D G V I Q C T E R D E F S Y
Rhesus Macaque Macaca mulatta XP_001102838 302 33815 T72 L D G V I Q C T E R D E F S Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64674 302 33976 T72 L D G V I Q C T E R D E F S Y
Rat Rattus norvegicus NP_445916 302 33978 T72 L D G V I Q C T E R D E F S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234728 243 27438 V53 D G G V L R E V V K H P T V E
Frog Xenopus laevis NP_001084875 290 32833 I72 E F S Y Q E M I A N L P L C S
Zebra Danio Brachydanio rerio NP_957328 289 32822 I71 E F S Y Q E M I A N L P L C C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120306 293 32592 Q68 E R D E F S Y Q E M I A F L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796573 284 31888 I71 E F S Y Q E M I T F L P L N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZUB3 334 36535 T99 L D G V I Q L T E R D E C A Y
Baker's Yeast Sacchar. cerevisiae Q12074 293 33306 I78 E F A Y Q E M I A H L A L N S
Red Bread Mold Neurospora crassa Q9Y8H7 291 33056 S71 C T E R D E F S Y Q E M I T H
Conservation
Percent
Protein Identity: 100 99.6 99.6 N.A. N.A. 94.6 95.3 N.A. N.A. 66.2 82.7 76.1 N.A. N.A. 57.6 N.A. 64.2
Protein Similarity: 100 100 99.6 N.A. N.A. 97.6 98 N.A. N.A. 73.8 91.7 88.7 N.A. N.A. 74.1 N.A. 81.1
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 13.3 0 0 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 33.3 6.6 6.6 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 47 54.9 57.2
Protein Similarity: N.A. N.A. N.A. 65.8 76.1 78.4
P-Site Identity: N.A. N.A. N.A. 80 0 0
P-Site Similarity: N.A. N.A. N.A. 86.6 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 24 0 0 16 0 8 0 % A
% Cys: 8 0 0 0 0 0 39 0 0 0 0 0 8 16 8 % C
% Asp: 8 47 8 0 8 0 0 0 0 0 47 0 0 0 0 % D
% Glu: 39 0 8 8 0 39 8 0 54 0 8 47 0 0 8 % E
% Phe: 0 31 0 0 8 0 8 0 0 8 0 0 47 0 0 % F
% Gly: 0 8 54 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 8 % H
% Ile: 0 0 0 0 47 0 0 31 0 0 8 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 47 0 0 0 8 0 8 0 0 0 31 0 31 8 0 % L
% Met: 0 0 0 0 0 0 31 0 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 16 0 0 0 16 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 31 0 0 8 % P
% Gln: 0 0 0 0 31 47 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 8 0 0 0 47 0 0 0 0 0 % R
% Ser: 0 0 24 0 0 8 0 8 0 0 0 0 0 39 24 % S
% Thr: 0 8 0 0 0 0 0 47 8 0 0 0 8 8 0 % T
% Val: 0 0 0 54 0 0 0 8 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 31 0 0 8 0 8 0 0 0 0 0 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _