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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRM All Species: 30.61
Human Site: Y48 Identified Species: 56.11
UniProt: P19623 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19623 NP_003123.2 302 33825 Y48 L H H R R S R Y Q D I L V F R
Chimpanzee Pan troglodytes XP_514381 302 33806 Y48 L H H R R S R Y Q D I L V F R
Rhesus Macaque Macaca mulatta XP_001102838 302 33815 Y48 L H H R R S R Y Q D I L V F R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64674 302 33976 Y48 L H H R R S R Y Q D I L V F R
Rat Rattus norvegicus NP_445916 302 33978 Y48 L H H R R S R Y Q D I L V F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234728 243 27438 H29 L L A L T S H H S E P M G V L
Frog Xenopus laevis NP_001084875 290 32833 Y48 L V L R S K T Y G N V L V L D
Zebra Danio Brachydanio rerio NP_957328 289 32822 Y47 M V F K S K T Y G N V L I L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120306 293 32592 T44 Q D V M V L E T K S H G R T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796573 284 31888 Y47 L V F K S K T Y G N V L V L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZUB3 334 36535 Y75 L F Q G K S D Y Q D V I V F Q
Baker's Yeast Sacchar. cerevisiae Q12074 293 33306 Y54 L I F K S T T Y G N V L V L D
Red Bread Mold Neurospora crassa Q9Y8H7 291 33056 F47 L Y Q D V L I F K S T D H G N
Conservation
Percent
Protein Identity: 100 99.6 99.6 N.A. N.A. 94.6 95.3 N.A. N.A. 66.2 82.7 76.1 N.A. N.A. 57.6 N.A. 64.2
Protein Similarity: 100 100 99.6 N.A. N.A. 97.6 98 N.A. N.A. 73.8 91.7 88.7 N.A. N.A. 74.1 N.A. 81.1
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 13.3 33.3 13.3 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. N.A. 33.3 46.6 46.6 N.A. N.A. 6.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 47 54.9 57.2
Protein Similarity: N.A. N.A. N.A. 65.8 76.1 78.4
P-Site Identity: N.A. N.A. N.A. 46.6 26.6 6.6
P-Site Similarity: N.A. N.A. N.A. 73.3 53.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 8 0 0 47 0 8 0 0 31 % D
% Glu: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % E
% Phe: 0 8 24 0 0 0 0 8 0 0 0 0 0 47 0 % F
% Gly: 0 0 0 8 0 0 0 0 31 0 0 8 8 8 0 % G
% His: 0 39 39 0 0 0 8 8 0 0 8 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 0 0 39 8 8 0 0 % I
% Lys: 0 0 0 24 8 24 0 0 16 0 0 0 0 0 0 % K
% Leu: 85 8 8 8 0 16 0 0 0 0 0 70 0 31 16 % L
% Met: 8 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 31 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 8 0 16 0 0 0 0 0 47 0 0 0 0 0 8 % Q
% Arg: 0 0 0 47 39 0 39 0 0 0 0 0 8 0 39 % R
% Ser: 0 0 0 0 31 54 0 0 8 16 0 0 0 0 0 % S
% Thr: 0 0 0 0 8 8 31 8 0 0 8 0 0 8 0 % T
% Val: 0 24 8 0 16 0 0 0 0 0 39 0 70 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _