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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A1 All Species: 22.12
Human Site: S729 Identified Species: 40.56
UniProt: P19634 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19634 NP_003038.2 815 90763 S729 A S P Q S P E S V D L V N E E
Chimpanzee Pan troglodytes XP_513239 793 88468 S716 A S P Q S P E S V D L V N E E
Rhesus Macaque Macaca mulatta XP_001115213 427 46791 G360 I M A L I A S G V V M R P Y V
Dog Lupus familis XP_535345 816 90951 S730 A S P Q S P E S V D L V N E E
Cat Felis silvestris
Mouse Mus musculus Q61165 820 91449 S733 A S P Q S P E S V D L V N E E
Rat Rattus norvegicus P26431 820 91629 S733 A S P Q S P E S V D L V N E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514675 940 104115 Q856 K R I Q T Q S Q M E W R N E V
Chicken Gallus gallus Q5ZJ75 574 64115 Y507 S E L T E G E Y E A Q Y I K R
Frog Xenopus laevis NP_001081553 781 87800 S709 I D P A S P E S V D T V N E T
Zebra Danio Brachydanio rerio NP_001106952 653 73606 L586 S Y S R H T L L P D A E E D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 M600 L D R K L H E M N R P S V Q I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 E468 Y M T S Y D D E D T P P G S G
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 E566 F G G L N E T E N T S P N P A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.3 51.9 95.8 N.A. 92.4 93.2 N.A. 42.5 21.7 73.2 55.4 N.A. N.A. N.A. 33.1 N.A.
Protein Similarity: 100 86.9 52 97.5 N.A. 95 95.1 N.A. 57.7 39.7 81.8 68.9 N.A. N.A. N.A. 52.5 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 20 6.6 66.6 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 40 20 66.6 33.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.3 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 35.5 41.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 8 8 0 8 0 0 0 8 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 0 0 8 8 0 8 54 0 0 0 8 8 % D
% Glu: 0 8 0 0 8 8 62 16 8 8 0 8 8 54 39 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 0 8 0 8 0 0 0 0 8 0 8 % G
% His: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 8 0 8 0 0 0 0 0 0 0 8 0 8 % I
% Lys: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 8 0 8 16 8 0 8 8 0 0 39 0 0 0 0 % L
% Met: 0 16 0 0 0 0 0 8 8 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 16 0 0 0 62 0 0 % N
% Pro: 0 0 47 0 0 47 0 0 8 0 16 16 8 8 0 % P
% Gln: 0 0 0 47 0 8 0 8 0 0 8 0 0 8 0 % Q
% Arg: 0 8 8 8 0 0 0 0 0 8 0 16 0 0 8 % R
% Ser: 16 39 8 8 47 0 16 47 0 0 8 8 0 8 0 % S
% Thr: 0 0 8 8 8 8 8 0 0 16 8 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 54 8 0 47 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 8 8 0 0 8 0 0 8 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _