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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A1
All Species:
18.79
Human Site:
Y557
Identified Species:
34.44
UniProt:
P19634
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19634
NP_003038.2
815
90763
Y557
L
N
R
F
N
K
K
Y
V
K
K
C
L
I
A
Chimpanzee
Pan troglodytes
XP_513239
793
88468
K556
L
I
A
G
E
R
S
K
E
P
Q
L
I
A
F
Rhesus Macaque
Macaca mulatta
XP_001115213
427
46791
N200
A
V
V
G
T
L
W
N
A
F
F
L
G
G
L
Dog
Lupus familis
XP_535345
816
90951
Y558
L
N
R
F
N
K
K
Y
V
K
K
C
L
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
Y561
L
N
R
F
N
K
K
Y
V
K
K
C
L
I
A
Rat
Rattus norvegicus
P26431
820
91629
Y561
L
N
R
F
N
K
K
Y
V
K
K
C
L
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514675
940
104115
K664
K
F
K
K
F
D
D
K
Y
L
R
R
L
L
I
Chicken
Gallus gallus
Q5ZJ75
574
64115
V347
M
Q
Q
T
L
R
T
V
A
F
M
C
E
T
C
Frog
Xenopus laevis
NP_001081553
781
87800
Y537
L
N
R
F
N
K
T
Y
V
K
K
C
L
I
A
Zebra Danio
Brachydanio rerio
NP_001106952
653
73606
T426
L
F
L
T
A
V
I
T
V
I
F
F
T
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
P440
L
Q
G
I
T
I
R
P
L
V
N
F
L
K
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
V308
S
A
N
S
Q
R
F
V
S
A
F
F
H
L
I
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
R406
Q
F
V
N
W
I
Y
R
V
K
T
I
R
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
51.9
95.8
N.A.
92.4
93.2
N.A.
42.5
21.7
73.2
55.4
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
100
86.9
52
97.5
N.A.
95
95.1
N.A.
57.7
39.7
81.8
68.9
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
6.6
6.6
93.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
0
100
N.A.
100
100
N.A.
26.6
26.6
93.3
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
8
0
0
0
16
8
0
0
0
8
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
8
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
24
0
39
8
0
8
0
0
16
24
24
0
0
16
% F
% Gly:
0
0
8
16
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
8
0
16
8
0
0
8
0
8
8
39
24
% I
% Lys:
8
0
8
8
0
39
31
16
0
47
39
0
0
8
0
% K
% Leu:
62
0
8
0
8
8
0
0
8
8
0
16
54
16
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
39
8
8
39
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
8
16
8
0
8
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
39
0
0
24
8
8
0
0
8
8
8
0
0
% R
% Ser:
8
0
0
8
0
0
8
0
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
16
16
0
16
8
0
0
8
0
8
8
0
% T
% Val:
0
8
16
0
0
8
0
16
54
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
39
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _