KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RXRA
All Species:
24.85
Human Site:
S225
Identified Species:
54.67
UniProt:
P19793
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19793
NP_002948.1
462
50811
S225
N
E
V
E
S
T
S
S
A
N
E
D
M
P
V
Chimpanzee
Pan troglodytes
XP_520345
601
65317
S364
N
E
V
E
S
T
S
S
A
N
E
D
M
P
V
Rhesus Macaque
Macaca mulatta
XP_001118265
450
49266
S215
N
E
V
E
S
T
S
S
A
N
E
D
M
P
V
Dog
Lupus familis
XP_858806
399
44519
M183
E
T
Y
V
D
A
N
M
G
L
N
P
N
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P28700
467
51198
S230
N
E
V
E
S
T
S
S
A
N
E
D
M
P
V
Rat
Rattus norvegicus
Q05343
467
51247
S230
N
E
V
E
S
T
S
S
A
N
E
D
M
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506054
433
47639
P202
S
S
A
N
E
D
M
P
V
E
K
I
L
E
A
Chicken
Gallus gallus
P28701
467
51215
G233
N
E
A
E
S
T
S
G
G
S
E
D
M
P
V
Frog
Xenopus laevis
P51128
488
53451
S251
N
E
V
E
S
S
N
S
A
N
E
D
M
P
V
Zebra Danio
Brachydanio rerio
A2T929
430
47452
E205
M
P
V
E
K
I
L
E
A
E
L
A
V
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20153
508
55226
S235
D
F
M
T
N
S
V
S
R
D
F
S
I
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
90.6
83.7
N.A.
97.4
97.4
N.A.
91.3
72.1
84.2
85
N.A.
42.7
N.A.
N.A.
N.A.
Protein Similarity:
100
76.7
91.9
84.4
N.A.
98
98.5
N.A.
92.6
83
88.9
88.3
N.A.
59.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
73.3
86.6
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
20
80
100
26.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
10
0
0
64
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
10
0
0
0
10
0
64
0
0
0
% D
% Glu:
10
64
0
73
10
0
0
10
0
19
64
0
0
28
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
19
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
10
10
0
10
0
0
% L
% Met:
10
0
10
0
0
0
10
10
0
0
0
0
64
0
0
% M
% Asn:
64
0
0
10
10
0
19
0
0
55
10
0
10
0
0
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
10
0
64
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% R
% Ser:
10
10
0
0
64
19
55
64
0
10
0
10
0
10
0
% S
% Thr:
0
10
0
10
0
55
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
64
10
0
0
10
0
10
0
0
0
10
0
73
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _