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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RXRA All Species: 27.27
Human Site: Y249 Identified Species: 60
UniProt: P19793 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19793 NP_002948.1 462 50811 Y249 V E P K T E T Y V E A N M G L
Chimpanzee Pan troglodytes XP_520345 601 65317 Y388 V E P K T E T Y V E A N M G L
Rhesus Macaque Macaca mulatta XP_001118265 450 49266 Y239 V E P K T E T Y V E A N M G L
Dog Lupus familis XP_858806 399 44519 Q201 D P V T N I C Q A A D K Q L F
Cat Felis silvestris
Mouse Mus musculus P28700 467 51198 Y254 V E P K T E T Y V E A N M G L
Rat Rattus norvegicus Q05343 467 51247 Y254 V E P K T E T Y V E A N M G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506054 433 47639 Y220 V E P K T E T Y I E A N M G L
Chicken Gallus gallus P28701 467 51215 T254 E L A V E P K T E A Y S D V N
Frog Xenopus laevis P51128 488 53451 Y275 V E P K T E T Y T E A N M G L
Zebra Danio Brachydanio rerio A2T929 430 47452 P223 T Y I E T N V P M P S N S P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20153 508 55226 L262 G D R A L T F L R V G P Y S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.5 90.6 83.7 N.A. 97.4 97.4 N.A. 91.3 72.1 84.2 85 N.A. 42.7 N.A. N.A. N.A.
Protein Similarity: 100 76.7 91.9 84.4 N.A. 98 98.5 N.A. 92.6 83 88.9 88.3 N.A. 59.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 93.3 0 93.3 13.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 100 100 N.A. 100 6.6 93.3 33.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 10 19 64 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 0 0 10 0 10 0 0 % D
% Glu: 10 64 0 10 10 64 0 0 10 64 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 10 0 0 64 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 64 0 0 10 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 10 0 0 10 0 0 0 0 0 10 64 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 64 0 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 73 0 0 19 % N
% Pro: 0 10 64 0 0 10 0 10 0 10 0 10 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 10 10 10 10 0 % S
% Thr: 10 0 0 10 73 10 64 10 10 0 0 0 0 0 10 % T
% Val: 64 0 10 10 0 0 10 0 46 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 64 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _