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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITIH2 All Species: 23.94
Human Site: S736 Identified Species: 58.52
UniProt: P19823 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19823 NP_002207.2 946 106463 S736 N L V S D P E S G I V V N G Q
Chimpanzee Pan troglodytes XP_001172570 890 99706 S703 D K R G S P D S K T R K T Y F
Rhesus Macaque Macaca mulatta XP_001107718 946 106162 S736 N L V S D P E S G I V I N G Q
Dog Lupus familis XP_535195 946 106900 S736 N L V S D P E S G I L V N G E
Cat Felis silvestris
Mouse Mus musculus Q61703 946 105909 S736 S L V S D P E S G I V V N G Q
Rat Rattus norvegicus Q63416 887 99079 Y705 S S R T G K T Y F G K L G I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515962 948 106412 L738 N L V S D P G L G I V V N G E
Chicken Gallus gallus NP_001124213 948 106749 T738 N L V S D P S T G V V V N G Q
Frog Xenopus laevis NP_001088330 935 104948 Q725 N L V S D P K Q G I T V N G K
Zebra Danio Brachydanio rerio XP_693183 963 108893 T755 N L V R D P L T G I M V N G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38 97 86.7 N.A. 83.9 39.6 N.A. 73.8 65.3 58.4 37.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 58.7 98.6 93.6 N.A. 91.7 60.1 N.A. 85.7 81 75.4 57.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 93.3 86.6 N.A. 93.3 0 N.A. 80 80 73.3 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 20 N.A. 86.6 93.3 86.6 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 80 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 40 0 0 0 0 0 0 0 20 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % F
% Gly: 0 0 0 10 10 0 10 0 80 10 0 0 10 80 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 70 0 10 0 10 0 % I
% Lys: 0 10 0 0 0 10 10 0 10 0 10 10 0 0 10 % K
% Leu: 0 80 0 0 0 0 10 10 0 0 10 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 70 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % N
% Pro: 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 50 % Q
% Arg: 0 0 20 10 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 20 10 0 70 10 0 10 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 10 20 0 10 10 0 10 0 0 % T
% Val: 0 0 80 0 0 0 0 0 0 10 50 70 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _