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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITIH2
All Species:
11.52
Human Site:
S756
Identified Species:
28.15
UniProt:
P19823
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19823
NP_002207.2
946
106463
S756
K
P
N
N
G
K
L
S
T
Y
F
G
K
L
G
Chimpanzee
Pan troglodytes
XP_001172570
890
99706
M720
L
G
I
A
N
A
Q
M
D
F
Q
V
E
V
T
Rhesus Macaque
Macaca mulatta
XP_001107718
946
106162
S756
K
P
N
N
G
K
L
S
T
Y
F
G
K
L
G
Dog
Lupus familis
XP_535195
946
106900
R756
K
P
K
N
E
K
L
R
T
Y
F
G
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61703
946
105909
S756
R
A
E
N
G
K
L
S
T
Y
F
G
K
L
G
Rat
Rattus norvegicus
Q63416
887
99079
I720
N
A
W
M
D
F
R
I
E
V
T
T
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515962
948
106412
S758
M
R
K
N
Q
K
L
S
T
Y
F
G
K
L
A
Chicken
Gallus gallus
NP_001124213
948
106749
N758
K
E
E
N
K
K
L
N
T
Y
F
G
K
F
G
Frog
Xenopus laevis
NP_001088330
935
104948
N745
K
A
K
S
G
K
L
N
T
Y
F
G
T
I
G
Zebra Danio
Brachydanio rerio
XP_693183
963
108893
H776
I
I
P
G
S
K
L
H
T
Y
F
G
R
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38
97
86.7
N.A.
83.9
39.6
N.A.
73.8
65.3
58.4
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.7
98.6
93.6
N.A.
91.7
60.1
N.A.
85.7
81
75.4
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
80
N.A.
80
0
N.A.
66.6
66.6
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
80
N.A.
86.6
6.6
N.A.
66.6
73.3
80
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
10
0
10
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
20
0
10
0
0
0
10
0
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
80
0
0
20
0
% F
% Gly:
0
10
0
10
40
0
0
0
0
0
0
80
0
0
70
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
0
0
10
0
0
0
0
0
10
10
% I
% Lys:
50
0
30
0
10
80
0
0
0
0
0
0
60
10
0
% K
% Leu:
10
0
0
0
0
0
80
0
0
0
0
0
0
50
0
% L
% Met:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
10
0
20
60
10
0
0
20
0
0
0
0
0
0
0
% N
% Pro:
0
30
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
10
10
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
10
10
0
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
80
0
10
10
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _