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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITIH1
All Species:
4.55
Human Site:
S590
Identified Species:
11.11
UniProt:
P19827
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19827
NP_002206.2
911
101389
S590
R
E
E
R
A
N
L
S
S
Q
A
L
Q
M
S
Chimpanzee
Pan troglodytes
XP_001172464
911
101406
S590
R
E
E
R
A
N
L
S
S
Q
A
L
R
M
S
Rhesus Macaque
Macaca mulatta
XP_001084712
794
88305
A476
R
A
N
L
S
S
Q
A
L
R
M
S
L
D
Y
Dog
Lupus familis
XP_533794
910
100979
A589
G
K
E
K
A
D
A
A
A
K
A
L
Q
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61702
907
101064
L586
E
G
E
E
R
A
N
L
S
S
Q
V
L
K
M
Rat
Rattus norvegicus
Q63416
887
99079
L566
A
Y
L
T
I
E
Q
L
L
E
K
R
K
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515962
948
106412
E621
T
I
L
Q
M
S
L
E
H
H
I
V
T
P
L
Chicken
Gallus gallus
XP_414253
886
99843
L565
A
Y
L
T
I
E
Q
L
L
E
K
R
I
A
A
Frog
Xenopus laevis
NP_001088330
935
104948
L608
R
N
I
T
Q
T
I
L
Q
M
S
I
D
H
H
Zebra Danio
Brachydanio rerio
XP_693183
963
108893
L639
A
E
A
L
S
L
S
L
R
Y
N
F
V
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
84
82.6
N.A.
81.8
52.9
N.A.
37.5
49.6
36.9
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
85.1
91.4
N.A.
90.7
70.1
N.A.
56.5
68.7
56.5
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
46.6
N.A.
13.3
0
N.A.
6.6
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
86.6
N.A.
20
20
N.A.
26.6
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
10
10
0
30
10
10
20
10
0
30
0
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
10
10
0
% D
% Glu:
10
30
40
10
0
20
0
10
0
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
10
% H
% Ile:
0
10
10
0
20
0
10
0
0
0
10
10
10
0
0
% I
% Lys:
0
10
0
10
0
0
0
0
0
10
20
0
10
10
0
% K
% Leu:
0
0
30
20
0
10
30
50
30
0
0
30
20
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
10
10
0
0
30
10
% M
% Asn:
0
10
10
0
0
20
10
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
10
10
0
30
0
10
20
10
0
20
0
0
% Q
% Arg:
40
0
0
20
10
0
0
0
10
10
0
20
10
0
0
% R
% Ser:
0
0
0
0
20
20
10
20
30
10
10
10
0
0
30
% S
% Thr:
10
0
0
30
0
10
0
0
0
0
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
20
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _