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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITIH1 All Species: 22.42
Human Site: S849 Identified Species: 54.81
UniProt: P19827 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19827 NP_002206.2 911 101389 S849 V S D I H P G S D P T K P D A
Chimpanzee Pan troglodytes XP_001172464 911 101406 S849 V S D I R P G S D P T K P D A
Rhesus Macaque Macaca mulatta XP_001084712 794 88305 P734 D I H P G S D P T K L D A T M
Dog Lupus familis XP_533794 910 100979 S848 V S D P H P G S D P T K T D A
Cat Felis silvestris
Mouse Mus musculus Q61702 907 101064 S845 V F D L H P G S D P T K T D A
Rat Rattus norvegicus Q63416 887 99079 S825 V F D V R P G S D P M K P D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515962 948 106412 K880 I Y N E R P G K D P K K P E A
Chicken Gallus gallus XP_414253 886 99843 S824 I L E I H S G S D P K K P D A
Frog Xenopus laevis NP_001088330 935 104948 T867 V Y D V R A G T D P E K P I A
Zebra Danio Brachydanio rerio XP_693183 963 108893 K898 V S D L F P G K D A D K Q D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 84 82.6 N.A. 81.8 52.9 N.A. 37.5 49.6 36.9 41.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 85.1 91.4 N.A. 90.7 70.1 N.A. 56.5 68.7 56.5 62.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 86.6 N.A. 80 73.3 N.A. 46.6 66.6 53.3 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 0 86.6 N.A. 86.6 80 N.A. 66.6 80 66.6 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 10 0 0 10 0 90 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 70 0 0 0 10 0 90 0 10 10 0 70 0 % D
% Glu: 0 0 10 10 0 0 0 0 0 0 10 0 0 10 0 % E
% Phe: 0 20 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 90 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 40 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 10 0 30 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 20 0 10 20 90 0 0 0 % K
% Leu: 0 10 0 20 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 20 0 70 0 10 0 80 0 0 60 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 40 0 0 0 20 0 60 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 10 0 40 0 20 10 0 % T
% Val: 70 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _