Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEL All Species: 2.42
Human Site: S533 Identified Species: 5.33
UniProt: P19835 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19835 NP_001798.2 753 79322 S533 G S S S M K R S L R T N F L R
Chimpanzee Pan troglodytes XP_001139049 813 91561 P612 S T T T K V P P P D M T S F P
Rhesus Macaque Macaca mulatta XP_001118455 713 76189 T533 L T Y V A L P T V T D Q E A T
Dog Lupus familis XP_548401 709 75901 H533 D H N S L K Q H L R T D Y L R
Cat Felis silvestris
Mouse Mus musculus Q64285 599 65794 I446 S H P S R M P I Y P K W M G A
Rat Rattus norvegicus P07882 612 67021 Q460 A D H A D D L Q Y V F G K P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516372 816 91960 Y606 N L N E I F Q Y V S T T T K V
Chicken Gallus gallus NP_001013015 556 61172 V404 Q Q V M K R T V V D L A T D Y
Frog Xenopus laevis NP_001080853 553 60703 N400 G P N P E Q E N M K R T V I D
Zebra Danio Brachydanio rerio NP_001020344 550 60357 K398 P N K E D I K K T V V E M E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P38433 620 71415 H468 P E W M G V L H G Y E I N F I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 84.4 78.7 N.A. 64.5 65.5 N.A. 26.1 48.8 48.3 43.5 N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: 100 41.2 88.3 86.3 N.A. 71.5 72.7 N.A. 41.1 57.5 57.9 53.1 N.A. N.A. N.A. 38.6 N.A.
P-Site Identity: 100 0 0 46.6 N.A. 6.6 0 N.A. 6.6 0 6.6 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 20 20 80 N.A. 6.6 6.6 N.A. 33.3 13.3 46.6 13.3 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 0 0 0 0 0 0 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 19 10 0 0 0 19 10 10 0 10 10 % D
% Glu: 0 10 0 19 10 0 10 0 0 0 10 10 10 10 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 10 0 10 19 10 % F
% Gly: 19 0 0 0 10 0 0 0 10 0 0 10 0 10 0 % G
% His: 0 19 10 0 0 0 0 19 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 10 0 0 0 10 0 10 10 % I
% Lys: 0 0 10 0 19 19 10 10 0 10 10 0 10 10 0 % K
% Leu: 10 10 0 0 10 10 19 0 19 0 10 0 0 19 0 % L
% Met: 0 0 0 19 10 10 0 0 10 0 10 0 19 0 0 % M
% Asn: 10 10 28 0 0 0 0 10 0 0 0 10 10 0 0 % N
% Pro: 19 10 10 10 0 0 28 10 10 10 0 0 0 10 10 % P
% Gln: 10 10 0 0 0 10 19 10 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 10 10 10 0 0 19 10 0 0 0 19 % R
% Ser: 19 10 10 28 0 0 0 10 0 10 0 0 10 0 0 % S
% Thr: 0 19 10 10 0 0 10 10 10 10 28 28 19 0 19 % T
% Val: 0 0 10 10 0 19 0 10 28 19 10 0 10 0 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 10 19 10 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _