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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFKB1 All Species: 18.18
Human Site: S301 Identified Species: 36.36
UniProt: P19838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19838 NP_003989.2 968 105356 S301 W E G F G D F S P T D V H R Q
Chimpanzee Pan troglodytes XP_001168657 976 106346 S309 W E G F G D F S P T D V H R Q
Rhesus Macaque Macaca mulatta XP_001109228 968 105518 S301 W E G F G D F S P T D V H R Q
Dog Lupus familis XP_862878 904 96875 I287 D V H K Q Y A I V F R T P P Y
Cat Felis silvestris
Mouse Mus musculus P25799 971 105623 S299 W E G F G D F S P T D V H R Q
Rat Rattus norvegicus Q63369 522 56535
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514381 266 29283
Chicken Gallus gallus Q04861 984 108151 S306 W E G F G D F S P T D V H R Q
Frog Xenopus laevis O73630 958 105836 A283 W H A F G D F A P T D V H K Q
Zebra Danio Brachydanio rerio NP_001001840 902 98760 D284 I R F Y E E E D E W E A L G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P15330 999 111533 V315 L R R P S D G V T S E A L P F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999819 1125 124026 G310 W Q S L A E F G P T D V H R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.7 42.9 N.A. 86.7 47.3 N.A. 26 71.6 39.3 40.1 N.A. 22.8 N.A. N.A. 35.7
Protein Similarity: 100 99.1 99.1 56.8 N.A. 91.8 50.3 N.A. 27 82.7 56.2 54.4 N.A. 38.7 N.A. N.A. 52
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. 0 100 73.3 0 N.A. 6.6 N.A. N.A. 60
P-Site Similarity: 100 100 100 0 N.A. 100 0 N.A. 0 100 86.6 20 N.A. 20 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 0 9 9 0 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 59 0 9 0 0 59 0 0 0 9 % D
% Glu: 0 42 0 0 9 17 9 0 9 0 17 0 0 0 0 % E
% Phe: 0 0 9 50 0 0 59 0 0 9 0 0 0 0 9 % F
% Gly: 0 0 42 0 50 0 9 9 0 0 0 0 0 9 0 % G
% His: 0 9 9 0 0 0 0 0 0 0 0 0 59 0 0 % H
% Ile: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 9 0 0 9 0 0 0 0 0 0 0 0 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 0 59 0 0 0 9 17 0 % P
% Gln: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 59 % Q
% Arg: 0 17 9 0 0 0 0 0 0 0 9 0 0 50 0 % R
% Ser: 0 0 9 0 9 0 0 42 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 9 59 0 9 0 0 0 % T
% Val: 0 9 0 0 0 0 0 9 9 0 0 59 0 0 0 % V
% Trp: 59 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _