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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFKB1 All Species: 12.73
Human Site: S439 Identified Species: 25.45
UniProt: P19838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19838 NP_003989.2 968 105356 S439 H G T M D T E S K K D P E G C
Chimpanzee Pan troglodytes XP_001168657 976 106346 S447 H G T M D T E S K K D P E G C
Rhesus Macaque Macaca mulatta XP_001109228 968 105518 S439 H G T M D T E S K K D S E G C
Dog Lupus familis XP_862878 904 96875 G419 Q M A A G A P G V D A G E E A
Cat Felis silvestris
Mouse Mus musculus P25799 971 105623 F437 H G T I N T K F K N G P K D C
Rat Rattus norvegicus Q63369 522 56535 F43 D K E E D V G F Q D N L F L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514381 266 29283
Chicken Gallus gallus Q04861 984 108151 S444 V K K D E E S S D K Q S D K W
Frog Xenopus laevis O73630 958 105836 S417 H C S A T N S S E K N Q Q P S
Zebra Danio Brachydanio rerio NP_001001840 902 98760 A416 C G G F G G G A Q M S D S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P15330 999 111533 Q451 F Q L E E P M Q Q D Q E L P A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999819 1125 124026 S443 S V P Q Q I P S H Q S G V V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.7 42.9 N.A. 86.7 47.3 N.A. 26 71.6 39.3 40.1 N.A. 22.8 N.A. N.A. 35.7
Protein Similarity: 100 99.1 99.1 56.8 N.A. 91.8 50.3 N.A. 27 82.7 56.2 54.4 N.A. 38.7 N.A. N.A. 52
P-Site Identity: 100 100 93.3 6.6 N.A. 46.6 6.6 N.A. 0 13.3 20 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 6.6 N.A. 73.3 20 N.A. 0 26.6 46.6 20 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 17 0 9 0 9 0 0 9 0 0 0 25 % A
% Cys: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 34 % C
% Asp: 9 0 0 9 34 0 0 0 9 25 25 9 9 9 0 % D
% Glu: 0 0 9 17 17 9 25 0 9 0 0 9 34 9 9 % E
% Phe: 9 0 0 9 0 0 0 17 0 0 0 0 9 0 0 % F
% Gly: 0 42 9 0 17 9 17 9 0 0 9 17 0 25 0 % G
% His: 42 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 9 0 0 0 9 0 34 42 0 0 9 9 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 9 9 9 0 % L
% Met: 0 9 0 25 0 0 9 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 9 17 0 0 0 0 % N
% Pro: 0 0 9 0 0 9 17 0 0 0 0 25 0 25 9 % P
% Gln: 9 9 0 9 9 0 0 9 25 9 17 9 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 9 0 0 0 17 50 0 0 17 17 9 0 9 % S
% Thr: 0 0 34 0 9 34 0 0 0 0 0 0 0 0 0 % T
% Val: 9 9 0 0 0 9 0 0 9 0 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _