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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFKB1 All Species: 33.03
Human Site: T721 Identified Species: 66.06
UniProt: P19838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19838 NP_003989.2 968 105356 T721 S T T Y D G T T P L H I A A G
Chimpanzee Pan troglodytes XP_001168657 976 106346 T729 S T T Y D G T T P L H I A A G
Rhesus Macaque Macaca mulatta XP_001109228 968 105518 T721 S T T Y D G T T P L H I A A G
Dog Lupus familis XP_862878 904 96875 T675 A R T F A G N T P L H L A A G
Cat Felis silvestris
Mouse Mus musculus P25799 971 105623 T717 S T T Y D G T T P L H I A A G
Rat Rattus norvegicus Q63369 522 56535 P292 L K A A G A D P L V E N F E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514381 266 29283 V36 G Y N P G L L V H P E L N Y L
Chicken Gallus gallus Q04861 984 108151 T719 S T T Y D G T T P L H I A A G
Frog Xenopus laevis O73630 958 105836 T681 A K T Y G G N T P L H L A A S
Zebra Danio Brachydanio rerio NP_001001840 902 98760 S669 A C T Y G G N S P L H L A A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P15330 999 111533 T724 N R S I E A N T V Q T K P S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999819 1125 124026 S841 A V T F C G D S A L H L A S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.7 42.9 N.A. 86.7 47.3 N.A. 26 71.6 39.3 40.1 N.A. 22.8 N.A. N.A. 35.7
Protein Similarity: 100 99.1 99.1 56.8 N.A. 91.8 50.3 N.A. 27 82.7 56.2 54.4 N.A. 38.7 N.A. N.A. 52
P-Site Identity: 100 100 100 60 N.A. 100 0 N.A. 0 100 60 53.3 N.A. 6.6 N.A. N.A. 33.3
P-Site Similarity: 100 100 100 80 N.A. 100 6.6 N.A. 6.6 100 73.3 73.3 N.A. 33.3 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 9 9 9 17 0 0 9 0 0 0 75 67 0 % A
% Cys: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 42 0 17 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 17 0 0 9 0 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 9 0 0 0 34 75 0 0 0 0 0 0 0 0 50 % G
% His: 0 0 0 0 0 0 0 0 9 0 75 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 42 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 0 0 9 0 0 0 % K
% Leu: 9 0 0 0 0 9 9 0 9 75 0 42 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 34 0 0 0 0 9 9 0 0 % N
% Pro: 0 0 0 9 0 0 0 9 67 9 0 0 9 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 42 0 9 0 0 0 0 17 0 0 0 0 0 17 25 % S
% Thr: 0 42 75 0 0 0 42 67 0 0 9 0 0 0 9 % T
% Val: 0 9 0 0 0 0 0 9 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 59 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _