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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKB1
All Species:
19.09
Human Site:
Y285
Identified Species:
38.18
UniProt:
P19838
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19838
NP_003989.2
968
105356
Y285
D
D
I
Q
I
R
F
Y
E
E
E
E
N
G
G
Chimpanzee
Pan troglodytes
XP_001168657
976
106346
Y293
D
D
I
Q
I
R
F
Y
E
E
E
E
N
G
G
Rhesus Macaque
Macaca mulatta
XP_001109228
968
105518
Y285
D
D
I
Q
I
R
F
Y
E
E
E
E
N
G
G
Dog
Lupus familis
XP_862878
904
96875
Q271
E
D
D
E
N
G
W
Q
A
F
G
D
F
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P25799
971
105623
Y283
D
D
I
Q
I
R
F
Y
E
E
E
E
N
G
G
Rat
Rattus norvegicus
Q63369
522
56535
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514381
266
29283
Chicken
Gallus gallus
Q04861
984
108151
Y290
D
D
I
Q
I
R
F
Y
E
E
D
E
N
G
G
Frog
Xenopus laevis
O73630
958
105836
F268
K
D
D
I
E
V
Q
F
Y
E
D
D
E
N
G
Zebra Danio
Brachydanio rerio
NP_001001840
902
98760
D268
E
E
V
F
L
L
C
D
K
V
Q
K
D
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15330
999
111533
T299
R
Y
H
T
L
D
I
T
E
P
A
K
V
F
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999819
1125
124026
F293
E
D
I
Q
V
K
F
F
E
I
S
A
D
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.7
42.9
N.A.
86.7
47.3
N.A.
26
71.6
39.3
40.1
N.A.
22.8
N.A.
N.A.
35.7
Protein Similarity:
100
99.1
99.1
56.8
N.A.
91.8
50.3
N.A.
27
82.7
56.2
54.4
N.A.
38.7
N.A.
N.A.
52
P-Site Identity:
100
100
100
6.6
N.A.
100
0
N.A.
0
93.3
20
0
N.A.
6.6
N.A.
N.A.
40
P-Site Similarity:
100
100
100
33.3
N.A.
100
0
N.A.
0
100
40
53.3
N.A.
20
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
42
67
17
0
0
9
0
9
0
0
17
17
17
9
0
% D
% Glu:
25
9
0
9
9
0
0
0
59
50
34
42
9
0
0
% E
% Phe:
0
0
0
9
0
0
50
17
0
9
0
0
9
9
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
9
0
0
50
50
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
9
42
0
9
0
0
9
0
0
0
0
17
% I
% Lys:
9
0
0
0
0
9
0
0
9
0
0
17
0
0
0
% K
% Leu:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
42
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
0
0
50
0
0
9
9
0
0
9
0
0
0
9
% Q
% Arg:
9
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
9
9
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
42
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _