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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI3
All Species:
2.73
Human Site:
T34
Identified Species:
7.5
UniProt:
P19957
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19957
NP_002629.1
117
12270
T34
V
P
V
K
G
Q
D
T
V
K
G
R
V
P
F
Chimpanzee
Pan troglodytes
A4K2N9
123
13294
C34
K
G
E
K
S
G
G
C
P
P
D
D
G
P
C
Rhesus Macaque
Macaca mulatta
A4K2T2
123
13376
A36
E
K
W
G
G
C
P
A
D
D
G
P
C
L
L
Dog
Lupus familis
XP_534433
107
11019
T34
V
L
P
K
G
S
G
T
D
R
G
R
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P97430
131
14290
A38
I
K
I
G
A
C
P
A
K
K
P
A
Q
C
L
Rat
Rattus norvegicus
Q6IE40
78
8646
V8
M
W
P
N
S
I
L
V
L
T
V
L
L
I
S
Wallaby
Macropus eugenll
Q9N0L8
191
21115
L37
P
D
F
R
Q
V
L
L
D
R
R
D
C
K
Q
Platypus
Ornith. anatinus
XP_001515148
264
28030
K126
E
E
S
G
G
R
P
K
G
R
G
H
L
P
S
Chicken
Gallus gallus
XP_425699
116
12790
P34
V
Q
Q
L
T
P
L
P
L
K
R
S
S
S
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.8
31.7
65.8
N.A.
32
24.7
20.4
25
23.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.2
43
75.2
N.A.
41.2
36.7
30.3
35.2
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
53.3
N.A.
6.6
0
0
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
60
N.A.
20
20
13.3
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
23
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
23
0
12
0
0
0
0
23
12
12
% C
% Asp:
0
12
0
0
0
0
12
0
34
12
12
23
0
0
0
% D
% Glu:
23
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
0
34
45
12
23
0
12
0
45
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
12
0
12
0
0
12
0
0
0
0
0
0
0
12
0
% I
% Lys:
12
23
0
34
0
0
0
12
12
34
0
0
0
12
0
% K
% Leu:
0
12
0
12
0
0
34
12
23
0
0
12
23
12
23
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
23
0
0
12
34
12
12
12
12
12
0
45
0
% P
% Gln:
0
12
12
0
12
12
0
0
0
0
0
0
12
0
12
% Q
% Arg:
0
0
0
12
0
12
0
0
0
34
23
23
0
0
0
% R
% Ser:
0
0
12
0
23
12
0
0
0
0
0
12
12
12
23
% S
% Thr:
0
0
0
0
12
0
0
23
0
12
0
0
0
0
0
% T
% Val:
34
0
12
0
0
12
0
12
12
0
12
0
23
0
12
% V
% Trp:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _