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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TYMP All Species: 4.55
Human Site: S50 Identified Species: 20
UniProt: P19971 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19971 NP_001107227.1 482 49955 S50 K R D G G R L S E A D I R G F
Chimpanzee Pan troglodytes XP_515224 347 36022
Rhesus Macaque Macaca mulatta XP_001112886 482 49890 S50 K R D G G R L S E A D I R G F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99N42 471 49317 I48 R N F V H A V I D G R A Q D T
Rat Rattus norvegicus Q5FVR2 476 49883 V51 E A D I R N F V H A L M D G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694448 455 48998 L49 K S Q I G A M L M A I W Q K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.7 96.6 N.A. N.A. 80.5 80.5 N.A. N.A. N.A. N.A. 51.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.7 98.1 N.A. N.A. 86.3 86.5 N.A. N.A. N.A. N.A. 66.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 N.A. N.A. 0 20 N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 N.A. N.A. 26.6 33.3 N.A. N.A. N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 34 0 0 0 67 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 0 0 0 0 0 17 0 34 0 17 17 0 % D
% Glu: 17 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % E
% Phe: 0 0 17 0 0 0 17 0 0 0 0 0 0 0 34 % F
% Gly: 0 0 0 34 50 0 0 0 0 17 0 0 0 50 17 % G
% His: 0 0 0 0 17 0 0 0 17 0 0 0 0 0 0 % H
% Ile: 0 0 0 34 0 0 0 17 0 0 17 34 0 0 0 % I
% Lys: 50 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % K
% Leu: 0 0 0 0 0 0 34 17 0 0 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 17 0 17 0 0 17 0 0 0 % M
% Asn: 0 17 0 0 0 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 17 0 0 0 0 0 0 0 0 0 34 0 0 % Q
% Arg: 17 34 0 0 17 34 0 0 0 0 17 0 34 0 17 % R
% Ser: 0 17 0 0 0 0 0 34 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % T
% Val: 0 0 0 17 0 0 17 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _