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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2B1
All Species:
28.18
Human Site:
S580
Identified Species:
77.5
UniProt:
P20020
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20020
NP_001001323.1
1258
138755
S580
Y
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102031
1246
137092
S606
Y
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Dog
Lupus familis
XP_852421
1258
138717
S580
Y
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0K7
1198
132569
S559
Y
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Rat
Rattus norvegicus
P11505
1258
138701
S580
Y
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512183
1220
134488
S580
Y
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Chicken
Gallus gallus
XP_416133
1218
134426
S578
H
K
V
Y
T
F
N
S
V
R
K
S
M
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64806
1015
110754
S448
A
A
C
E
T
M
G
S
A
T
T
I
C
S
D
Baker's Yeast
Sacchar. cerevisiae
P38929
1173
130843
D552
F
K
K
G
N
R
E
D
D
E
D
Q
L
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.9
99.4
N.A.
79
99.3
N.A.
94.1
92
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
96.9
99.9
N.A.
86.9
99.7
N.A.
95.7
95
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
12
0
12
0
0
0
12
% D
% Glu:
0
0
0
12
0
0
12
0
0
12
0
0
0
0
0
% E
% Phe:
12
0
0
0
0
78
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
89
12
0
0
0
0
0
0
0
78
0
0
0
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
78
0
0
% M
% Asn:
0
0
0
0
12
0
78
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
78
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
89
0
0
0
78
0
89
0
% S
% Thr:
0
0
0
0
89
0
0
0
0
12
12
0
0
0
78
% T
% Val:
0
0
78
0
0
0
0
0
78
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
78
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _