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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HLA-DPA1 All Species: 10
Human Site: Y174 Identified Species: 44
UniProt: P20036 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20036 NP_291032.2 260 29381 Y174 L F L P R T D Y S F H K F H Y
Chimpanzee Pan troglodytes XP_518390 260 29476 Y174 L F L P R T D Y S F H K F H Y
Rhesus Macaque Macaca mulatta Q30631 254 28386 H168 V F L P R E D H L F R K F H Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P14434 256 28074 Y170 S F F V N R D Y S F H K L S Y
Rat Rattus norvegicus P20037 256 28583 Y170 S F L I N S D Y S F H K M A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510298 331 36062 H245 D F Y P R T D H S F R K F H Y
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 57.6 N.A. N.A. 59.2 56.1 N.A. 50.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 70.3 N.A. N.A. 71.9 68.8 N.A. 61.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 66.6 N.A. N.A. 53.3 60 N.A. 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 80 N.A. N.A. 53.3 66.6 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 100 17 0 0 0 0 0 0 100 0 0 67 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 34 0 0 67 0 0 67 0 % H
% Ile: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % K
% Leu: 34 0 67 0 0 0 0 0 17 0 0 0 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % M
% Asn: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 67 17 0 0 0 0 34 0 0 0 0 % R
% Ser: 34 0 0 0 0 17 0 0 84 0 0 0 0 17 0 % S
% Thr: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % T
% Val: 17 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 17 0 0 0 0 67 0 0 0 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _