KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD33
All Species:
5.15
Human Site:
S248
Identified Species:
22.67
UniProt:
P20138
Number Species:
5
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20138
NP_001763.3
364
39825
S248
G
I
F
P
G
D
G
S
G
K
Q
E
T
R
A
Chimpanzee
Pan troglodytes
Q64JA4
387
42507
T247
T
V
F
Q
G
D
G
T
A
S
T
T
L
R
N
Rhesus Macaque
Macaca mulatta
XP_001114616
415
45504
L299
N
P
R
T
D
I
F
L
G
D
G
S
G
K
Q
Dog
Lupus familis
XP_541460
697
77324
T395
S
I
F
Q
R
E
G
T
G
T
E
A
L
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q63994
403
44806
E248
L
V
L
V
A
V
G
E
A
T
V
K
L
L
I
Rat
Rattus norvegicus
P07722
626
69334
S247
P
V
I
V
E
M
N
S
S
V
E
A
I
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48
76.3
31.5
N.A.
40.9
20.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.9
79.2
40.3
N.A.
52.3
32.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
6.6
26.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
13.3
46.6
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
34
0
0
34
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
34
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
17
17
0
17
0
0
34
17
0
17
0
% E
% Phe:
0
0
50
0
0
0
17
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
34
0
67
0
50
0
17
0
17
17
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
17
0
0
17
0
0
0
0
0
0
17
0
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
17
0
17
0
17
0
% K
% Leu:
17
0
17
0
0
0
0
17
0
0
0
0
50
17
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
0
17
0
0
0
0
0
0
0
34
% N
% Pro:
17
17
0
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
34
0
0
0
0
0
0
17
0
0
0
17
% Q
% Arg:
0
0
17
0
17
0
0
0
0
0
0
0
0
34
0
% R
% Ser:
17
0
0
0
0
0
0
34
17
17
0
17
0
0
0
% S
% Thr:
17
0
0
17
0
0
0
34
0
34
17
17
17
0
0
% T
% Val:
0
50
0
34
0
17
0
0
0
17
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _