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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLK2
All Species:
14.55
Human Site:
T208
Identified Species:
64
UniProt:
P20151
Number Species:
5
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20151
NP_001002231.1
261
28671
T208
L
W
T
G
G
K
D
T
C
G
G
D
S
G
G
Chimpanzee
Pan troglodytes
XP_001174026
261
28658
T208
L
W
T
G
G
K
D
T
C
G
G
D
S
G
G
Rhesus Macaque
Macaca mulatta
P33619
261
28798
T208
S
W
M
G
G
K
S
T
C
S
G
D
S
G
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P15946
261
28709
T208
E
M
G
G
G
K
D
T
C
K
G
D
S
G
G
Rat
Rattus norvegicus
P36373
261
28954
T208
E
L
E
G
G
K
D
T
C
T
G
D
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90627
248
26051
D196
G
Y
L
N
G
G
K
D
S
C
Q
G
D
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
74.7
N.A.
N.A.
59.3
58.2
N.A.
N.A.
41
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
84.2
N.A.
N.A.
72.4
73.1
N.A.
N.A.
57.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
73.3
N.A.
N.A.
73.3
73.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
N.A.
N.A.
73.3
73.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
84
17
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
67
17
0
0
0
84
17
0
0
% D
% Glu:
34
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
17
84
100
17
0
0
0
34
84
17
0
84
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
84
17
0
0
17
0
0
0
0
0
% K
% Leu:
34
17
17
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
17
17
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
0
0
0
0
0
17
0
17
17
0
0
84
17
0
% S
% Thr:
0
0
34
0
0
0
0
84
0
17
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _