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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPINK2
All Species:
17.58
Human Site:
Y59
Identified Species:
48.33
UniProt:
P20155
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20155
NP_066937.1
84
9291
Y59
C
G
S
D
M
S
T
Y
A
N
E
C
T
L
C
Chimpanzee
Pan troglodytes
XP_001136884
134
13730
Y109
C
G
S
D
M
S
T
Y
A
N
E
C
T
L
C
Rhesus Macaque
Macaca mulatta
XP_001083400
81
9153
E59
D
M
I
T
Y
P
N
E
C
T
L
C
M
K
I
Dog
Lupus familis
XP_854200
94
10054
Y69
C
G
S
D
M
S
T
Y
P
N
E
C
T
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMY7
86
9704
Y61
C
G
T
D
M
N
T
Y
S
N
E
C
T
L
C
Rat
Rattus norvegicus
Q6IE49
86
9679
Y61
C
G
T
D
M
N
T
Y
G
N
E
C
T
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P85000
55
6014
E43
L
C
L
S
N
S
E
E
N
K
N
V
Q
I
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664393
77
8426
F63
C
M
L
C
M
E
I
F
E
T
N
V
N
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723689
68
7456
E56
V
L
D
C
L
I
K
E
G
R
S
I
T
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.1
75
64.8
N.A.
55.8
55.8
N.A.
N.A.
34.5
N.A.
44
N.A.
35.7
N.A.
N.A.
N.A.
Protein Similarity:
100
61.9
83.3
76.5
N.A.
69.7
69.7
N.A.
N.A.
45.2
N.A.
58.3
N.A.
54.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
80
80
N.A.
N.A.
6.6
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
93.3
N.A.
100
93.3
N.A.
N.A.
13.3
N.A.
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% A
% Cys:
67
12
0
23
0
0
0
0
12
0
0
67
0
0
56
% C
% Asp:
12
0
12
56
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
12
34
12
0
56
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
56
0
0
0
0
0
0
23
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
12
12
0
0
0
0
12
0
12
12
% I
% Lys:
0
0
0
0
0
0
12
0
0
12
0
0
0
12
0
% K
% Leu:
12
12
23
0
12
0
0
0
0
0
12
0
0
67
12
% L
% Met:
0
23
0
0
67
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
12
23
12
0
12
56
23
0
12
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
34
12
0
45
0
0
12
0
12
0
0
0
0
% S
% Thr:
0
0
23
12
0
0
56
0
0
23
0
0
67
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
23
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
56
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _