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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBP
All Species:
25.15
Human Site:
S48
Identified Species:
34.58
UniProt:
P20226
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20226
NP_003185.1
339
37698
S48
Q
P
I
Q
N
T
N
S
L
S
I
L
E
E
Q
Chimpanzee
Pan troglodytes
A6H907
376
41488
F81
A
S
N
P
D
T
A
F
N
S
N
P
E
V
K
Rhesus Macaque
Macaca mulatta
XP_001085250
288
31595
S48
Q
P
I
Q
N
T
N
S
L
S
I
L
E
E
Q
Dog
Lupus familis
XP_854525
324
35731
S48
Q
P
I
Q
N
T
N
S
L
S
L
L
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P29037
316
34691
S48
Q
P
I
Q
N
T
N
S
L
S
I
L
E
E
Q
Rat
Rattus norvegicus
A6H909
344
38336
N86
K
D
R
T
V
T
G
N
K
V
T
N
E
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
S48
Q
P
V
Q
S
T
N
S
L
S
I
L
E
E
Q
Frog
Xenopus laevis
P27633
297
32684
L48
P
V
Q
T
T
N
S
L
S
I
L
E
E
Q
Q
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
S48
Q
P
V
Q
N
S
N
S
L
S
L
L
E
E
Q
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
P62
E
L
D
L
S
F
L
P
D
D
L
S
T
Q
E
Fruit Fly
Dros. melanogaster
P20227
353
38433
P48
P
D
S
L
M
P
A
P
G
S
S
S
V
Q
H
Honey Bee
Apis mellifera
XP_623088
319
35720
Q48
Q
Q
Q
Q
Q
S
Q
Q
Q
Q
Q
S
Q
Q
Q
Nematode Worm
Caenorhab. elegans
P32085
340
36629
S65
Q
S
I
Q
P
M
Q
S
Q
Q
M
H
S
L
Q
Sea Urchin
Strong. purpuratus
P91809
265
29089
S26
Q
D
G
G
Q
Q
R
S
H
Y
P
Q
I
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
84.6
93.5
N.A.
91.1
50.2
N.A.
N.A.
87.9
81.4
80.8
58.7
58
61.6
52
59.5
Protein Similarity:
100
64
84.9
93.8
N.A.
91.4
63.6
N.A.
N.A.
88.5
84.6
84
67.5
67.4
66.9
60.8
65.4
P-Site Identity:
100
20
100
93.3
N.A.
100
20
N.A.
N.A.
86.6
13.3
80
0
6.6
20
33.3
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
33.3
N.A.
N.A.
100
33.3
100
33.3
13.3
40
40
13.3
Percent
Protein Identity:
N.A.
48.3
N.A.
47.7
48.6
N.A.
Protein Similarity:
N.A.
53.6
N.A.
52.5
57.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
18
6
0
6
0
0
0
6
6
0
0
0
0
0
% D
% Glu:
6
0
0
0
0
0
0
0
0
0
0
6
53
42
6
% E
% Phe:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
6
6
0
0
6
0
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
6
% H
% Ile:
0
0
30
0
0
0
0
0
0
6
24
0
6
0
0
% I
% Lys:
6
0
0
0
0
0
0
0
6
0
0
0
0
0
6
% K
% Leu:
0
6
0
12
0
0
6
6
36
0
24
36
0
6
0
% L
% Met:
0
0
0
0
6
6
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
6
0
30
6
36
6
6
0
6
6
0
0
0
% N
% Pro:
12
36
0
6
6
6
0
12
0
0
6
6
0
0
0
% P
% Gln:
53
6
12
48
12
6
12
6
12
12
6
6
6
24
53
% Q
% Arg:
0
0
6
0
0
0
6
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
6
0
12
12
6
48
6
48
6
18
6
6
12
% S
% Thr:
0
0
0
12
6
42
0
0
0
0
6
0
6
0
0
% T
% Val:
0
6
12
0
6
0
0
0
0
6
0
0
6
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _