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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBP
All Species:
17.88
Human Site:
T126
Identified Species:
24.58
UniProt:
P20226
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20226
NP_003185.1
339
37698
T126
P
Q
L
F
H
S
Q
T
L
T
T
A
P
L
P
Chimpanzee
Pan troglodytes
A6H907
376
41488
T163
S
Q
L
H
P
G
D
T
D
S
V
Q
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001085250
288
31595
P86
A
P
L
P
G
T
T
P
L
Y
P
S
P
V
T
Dog
Lupus familis
XP_854525
324
35731
T111
P
Q
L
F
H
S
Q
T
L
T
T
A
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P29037
316
34691
T103
P
Q
L
F
H
S
Q
T
L
T
T
A
P
L
P
Rat
Rattus norvegicus
A6H909
344
38336
A132
S
C
L
C
S
H
D
A
D
S
N
Q
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
T89
P
Q
L
F
H
S
Q
T
L
T
T
A
P
L
P
Frog
Xenopus laevis
P27633
297
32684
T86
L
F
H
P
Q
T
L
T
T
A
P
L
P
G
N
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
V89
L
Y
H
S
T
Q
A
V
S
T
T
T
A
L
P
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
Q110
P
A
A
T
F
D
Q
Q
N
P
S
L
L
G
G
Fruit Fly
Dros. melanogaster
P20227
353
38433
G140
M
S
E
R
S
V
G
G
S
G
A
G
G
G
G
Honey Bee
Apis mellifera
XP_623088
319
35720
M107
P
Q
T
P
Q
N
M
M
S
P
L
V
Q
N
T
Nematode Worm
Caenorhab. elegans
P32085
340
36629
L129
L
T
V
P
M
T
P
L
A
Y
S
V
Y
D
R
Sea Urchin
Strong. purpuratus
P91809
265
29089
S64
S
S
L
A
P
G
S
S
F
I
P
P
S
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
T39
D
G
T
K
P
A
T
T
F
Q
S
E
E
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
84.6
93.5
N.A.
91.1
50.2
N.A.
N.A.
87.9
81.4
80.8
58.7
58
61.6
52
59.5
Protein Similarity:
100
64
84.9
93.8
N.A.
91.4
63.6
N.A.
N.A.
88.5
84.6
84
67.5
67.4
66.9
60.8
65.4
P-Site Identity:
100
33.3
20
100
N.A.
100
6.6
N.A.
N.A.
100
13.3
26.6
13.3
0
13.3
0
6.6
P-Site Similarity:
100
40
40
100
N.A.
100
13.3
N.A.
N.A.
100
20
26.6
20
0
20
20
13.3
Percent
Protein Identity:
N.A.
48.3
N.A.
47.7
48.6
N.A.
Protein Similarity:
N.A.
53.6
N.A.
52.5
57.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
6
0
6
6
6
6
6
6
24
6
0
0
% A
% Cys:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
6
12
0
12
0
0
0
0
12
0
% D
% Glu:
0
0
6
0
0
0
0
0
0
0
0
6
6
0
0
% E
% Phe:
0
6
0
24
6
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
6
0
0
6
12
6
6
0
6
0
6
6
18
12
% G
% His:
0
0
12
6
24
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
6
% I
% Lys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
18
0
48
0
0
0
6
6
30
0
6
12
12
30
0
% L
% Met:
6
0
0
0
6
0
6
6
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
0
0
6
0
0
6
0
6
0
0
6
6
% N
% Pro:
36
6
0
24
18
0
6
6
0
12
18
6
42
6
36
% P
% Gln:
0
36
0
0
12
6
30
6
0
6
0
12
6
0
0
% Q
% Arg:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% R
% Ser:
18
12
0
6
12
24
6
6
18
12
18
6
6
12
6
% S
% Thr:
0
6
12
6
6
18
12
42
6
30
30
6
0
0
12
% T
% Val:
0
0
6
0
0
6
0
6
0
0
6
12
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
0
0
12
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _