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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBP
All Species:
14.55
Human Site:
T135
Identified Species:
20
UniProt:
P20226
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20226
NP_003185.1
339
37698
T135
T
T
A
P
L
P
G
T
T
P
L
Y
P
S
P
Chimpanzee
Pan troglodytes
A6H907
376
41488
K172
S
V
Q
P
S
P
E
K
P
N
S
D
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001085250
288
31595
M95
Y
P
S
P
V
T
P
M
T
P
I
T
P
A
T
Dog
Lupus familis
XP_854525
324
35731
T120
T
T
A
P
L
P
G
T
T
P
L
Y
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P29037
316
34691
T112
T
T
A
P
L
P
G
T
T
P
L
Y
P
S
P
Rat
Rattus norvegicus
A6H909
344
38336
T141
S
N
Q
L
S
S
E
T
P
N
S
N
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
T98
T
T
A
P
L
P
G
T
T
P
L
Y
P
S
P
Frog
Xenopus laevis
P27633
297
32684
P95
A
P
L
P
G
N
T
P
L
Y
P
S
P
I
T
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
N98
T
T
T
A
L
P
G
N
T
P
L
Y
T
T
P
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
V119
P
S
L
L
G
G
G
V
H
N
S
P
F
Y
S
Fruit Fly
Dros. melanogaster
P20227
353
38433
A149
G
A
G
G
G
G
D
A
L
S
N
I
H
Q
T
Honey Bee
Apis mellifera
XP_623088
319
35720
H116
P
L
V
Q
N
T
N
H
I
A
P
P
S
I
G
Nematode Worm
Caenorhab. elegans
P32085
340
36629
A138
Y
S
V
Y
D
R
D
A
L
T
H
Q
A
P
A
Sea Urchin
Strong. purpuratus
P91809
265
29089
P73
I
P
P
S
P
M
A
P
L
T
P
A
T
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
G8
M
A
E
P
G
L
E
G
S
Q
P
V
D
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
G8
M
A
D
Q
G
T
E
G
S
Q
P
V
D
L
T
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
R48
Q
S
E
E
D
I
K
R
A
A
P
E
S
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
84.6
93.5
N.A.
91.1
50.2
N.A.
N.A.
87.9
81.4
80.8
58.7
58
61.6
52
59.5
Protein Similarity:
100
64
84.9
93.8
N.A.
91.4
63.6
N.A.
N.A.
88.5
84.6
84
67.5
67.4
66.9
60.8
65.4
P-Site Identity:
100
13.3
26.6
100
N.A.
100
13.3
N.A.
N.A.
100
13.3
66.6
6.6
0
0
0
0
P-Site Similarity:
100
20
53.3
100
N.A.
100
20
N.A.
N.A.
100
13.3
73.3
13.3
0
0
6.6
0
Percent
Protein Identity:
N.A.
48.3
N.A.
47.7
48.6
N.A.
Protein Similarity:
N.A.
53.6
N.A.
52.5
57.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
18
24
6
0
0
6
12
6
12
0
6
12
6
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
12
0
12
0
0
0
0
6
12
0
0
% D
% Glu:
0
0
12
6
0
0
24
0
0
0
0
6
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
6
0
6
6
30
12
36
12
0
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
6
6
0
6
0
6
0
0
% H
% Ile:
6
0
0
0
0
6
0
0
6
0
6
6
0
12
0
% I
% Lys:
0
0
0
0
0
0
6
6
0
0
0
0
0
0
6
% K
% Leu:
0
6
12
12
30
6
0
0
24
0
30
0
0
24
0
% L
% Met:
12
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
6
6
6
6
0
18
6
6
0
0
0
% N
% Pro:
12
18
6
48
6
36
6
12
12
36
36
12
36
12
36
% P
% Gln:
6
0
12
12
0
0
0
0
0
12
0
6
0
6
0
% Q
% Arg:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% R
% Ser:
12
18
6
6
12
6
0
0
12
6
18
6
18
24
18
% S
% Thr:
30
30
6
0
0
18
6
30
36
12
0
6
12
6
24
% T
% Val:
0
6
12
0
6
0
0
6
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
6
0
0
0
0
0
6
0
30
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _