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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBP
All Species:
52.12
Human Site:
T276
Identified Species:
71.67
UniProt:
P20226
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20226
NP_003185.1
339
37698
T276
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Chimpanzee
Pan troglodytes
A6H907
376
41488
T313
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Rhesus Macaque
Macaca mulatta
XP_001085250
288
31595
T225
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Dog
Lupus familis
XP_854525
324
35731
T261
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
P29037
316
34691
T253
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Rat
Rattus norvegicus
A6H909
344
38336
T282
R
L
E
I
L
A
L
T
H
R
Q
F
S
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
T239
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Frog
Xenopus laevis
P27633
297
32684
T234
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
T239
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
T260
R
L
E
G
L
V
L
T
H
Q
Q
F
S
S
Y
Fruit Fly
Dros. melanogaster
P20227
353
38433
T290
R
L
E
G
L
V
L
T
H
C
N
F
S
S
Y
Honey Bee
Apis mellifera
XP_623088
319
35720
T257
R
L
E
G
L
V
L
T
H
G
Q
F
S
S
Y
Nematode Worm
Caenorhab. elegans
P32085
340
36629
G275
R
F
P
I
Q
L
E
G
L
C
I
T
H
S
Q
Sea Urchin
Strong. purpuratus
P91809
265
29089
H203
L
E
G
L
V
L
T
H
G
Q
F
S
S
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
G138
E
G
L
A
Y
S
H
G
A
F
S
S
Y
E
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
S138
E
G
L
A
Y
S
H
S
A
F
S
S
Y
E
P
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
S178
R
L
E
G
L
A
F
S
H
G
T
F
S
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
84.6
93.5
N.A.
91.1
50.2
N.A.
N.A.
87.9
81.4
80.8
58.7
58
61.6
52
59.5
Protein Similarity:
100
64
84.9
93.8
N.A.
91.4
63.6
N.A.
N.A.
88.5
84.6
84
67.5
67.4
66.9
60.8
65.4
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
N.A.
100
100
100
100
86.6
93.3
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
100
100
100
100
86.6
93.3
20
26.6
Percent
Protein Identity:
N.A.
48.3
N.A.
47.7
48.6
N.A.
Protein Similarity:
N.A.
53.6
N.A.
52.5
57.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
66.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
6.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
6
77
0
0
0
6
0
0
0
0
0
0
12
6
% E
% Phe:
0
6
0
0
0
0
6
0
0
12
6
77
0
0
0
% F
% Gly:
0
12
6
71
0
0
0
12
6
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
6
77
0
0
0
6
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
6
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
6
77
12
6
77
12
71
0
6
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% N
% Pro:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
6
0
0
0
0
59
65
0
0
0
6
% Q
% Arg:
83
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
12
0
0
12
18
83
83
0
% S
% Thr:
0
0
0
0
0
0
6
71
0
0
6
6
0
0
0
% T
% Val:
0
0
0
0
6
65
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
12
6
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _